Formoterol fumarate
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- Product name: Formoterol fumarate
- CAS: 43229-80-7
- MF: C42H52N4O12
- MW: 804.88
- EINECS:1308068-626-2
- MDL Number:MFCD03093863
- Synonyms:formamide,n-(2-hydroxy-5-(1-hydroxy-2-((2-(4-methoxyphenyl)-1-methylethyl)amin ;o)ethyl)phenyl)-,(e)-2-butenedioate(2:1)(salt),dihydrate ;(+/-)-(R*,R*)-N-[2-HYDROXY-5-[1-HYDROXY-2-[[2-(4-METHOXYPHENYL)-1-METHYLETHYL]AMINO]ETHYL]PHENYL] FORMAMIDE HEMIFUMARATE;(R*,R*)-(+)-N-[2-HYDROXY-5-[1-HYDROXY-2-[[2-(4-METHOXYPHENYL)-1-METHYLETHYL]AMINO]ETHYL]-PHENYL]FORMAMIDE FUMARATE;(R*,R*)-N-[2-HYDROXY-5-[1-HYDROXY-2-[[2-(4-METHOXYPHENYL)-1-METHYLETHYL]AMINO]ETHYL]PHENYL]FORMAMIDE FUMARATE;Formoterol fumarate JP13;Formoterol fumarate 50 gram;FORMATEROL FUMATATE
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Properties
Melting point :138-140°C
storage temp. :Room temperature
solubility :Slightly soluble in water, soluble in methanol, slightly soluble in 2-propanol, practically insoluble in acetonitrile.
pka :pKa1 7.9; pKa2 9.2(at 25℃)
form :Solid
color :White to off-white
λmax :284nm(lit.)
Merck :14,4245
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
storage temp. :Room temperature
solubility :Slightly soluble in water, soluble in methanol, slightly soluble in 2-propanol, practically insoluble in acetonitrile.
pka :pKa1 7.9; pKa2 9.2(at 25℃)
form :Solid
color :White to off-white
λmax :284nm(lit.)
Merck :14,4245
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety Information
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Description
Formoterol is an agonist of β-adrenergic receptors that activates the β1, β2, and β3 receptors with pEC50 values of 7.5, 9.0, and 6.8 respectively. It displays high selectivity for β-adrenoceptors in the trachea over those in atria. Formoterol activity is retained in the airway for extended periods, so it is classified as a long-acting β-receptor agonist. It has use, alone or in combination with other compounds, in chronic obstructive pulmonary disease and asthma.Related product price
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