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ChemicalBook > Product Catalogue >API >Digestive system drugs >Gastrointestinal antispasmodic drugs >Glycopyrrolate

Glycopyrrolate

Glycopyrrolate Structure
  • ₹9601.78 - ₹38829.28
  • Product name: Glycopyrrolate
  • CAS: 596-51-0
  • MF: C19H28BrNO3-
  • MW: 398.33
  • EINECS:209-887-0
  • MDL Number:MFCD00072137
  • Synonyms:1,1-dimethyl-3-hydroxypyrrolidiniumbromidealpha-cyclopentylmandelate ;1-methyl-3-pyrrolidylalpha-phenylcyclopentaneglycolatemethobromide ;ahr504 ;asecryl ;gastrodyn ;glycopyrrolatebromide ;nodapton ;pyrrolidinium,1,1-dimethyl-3-hydroxy-,bromide,alpha-cyclopentylmandelate
3 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • 100MG
  • ManufacturerTCI Chemicals (India)
  • Product numberG0392
  • Product descriptionGlycopyrrolate
  • Packaging100MG
  • Price₹10800
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0029
  • Product descriptionGlycopyrrolate ≥98% (HPLC)
  • Packaging5MG
  • Price₹9601.78
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0029
  • Product descriptionGlycopyrrolate ≥98% (HPLC)
  • Packaging25MG
  • Price₹38829.28
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) G0392 Glycopyrrolate 100MG ₹10800 2022-05-26 Buy
Sigma-Aldrich(India) SML0029 Glycopyrrolate ≥98% (HPLC) 5MG ₹9601.78 2022-06-14 Buy
Sigma-Aldrich(India) SML0029 Glycopyrrolate ≥98% (HPLC) 25MG ₹38829.28 2022-06-14 Buy

Properties

Melting point :192-195°C
Density :1.3222 (rough estimate)
refractive index :1.6200 (estimate)
storage temp. :2-8°C
solubility :H2O: ≥24mg/mL
form :powder
color :white to tan
Merck :14,4501
Stability :Hygroscopic
InChI :InChI=1S/C19H28NO3.BrH/c1-20(2)13-12-17(14-20)23-18(21)19(22,16-10-6-7-11-16)15-8-4-3-5-9-15;/h3-5,8-9,16-17,22H,6-7,10-14H2,1-2H3;1H/q+1;/p-1
InChIKey :VPNYRYCIDCJBOM-UHFFFAOYSA-M
SMILES :C(O)(C(=O)OC1CC[N+](C)(C)C1)(C1=CC=CC=C1)C1CCCC1.[Br-]
CAS DataBase Reference :596-51-0(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Glycopyrrolate is an antagonist of muscarinic acetylcholine receptors (mAChRs; Kis = 0.42, 1.77, 0.52, 0.78, and 1.29 nM for the M1-M5 receptors, respectively). It induces relaxation of precontracted isolated human bronchi when used at concentrations of 0.01, 0.1, or 1 μM. Glycopyrrolate reduces post-prandial gastric antral motility in dogs when administered at a dose of 0.01 mg/kg. It inhibits salivation in a rat model of sialorrhea induced by pilocarpine with an ED50 value of 0.74 μg/kg. Formulations containing glycopyrrolate have been used in the treatment of sialorrhea, peptic ulcers, and chronic obstructive pulmonary disease (COPD).

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