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ChemicalBook > Product Catalogue >API >Anesthetic Agents >General anesthetics >Halothane

Halothane

Halothane Structure
  • ₹0
  • Product name: Halothane
  • CAS: 151-67-7
  • MF: C2HBrClF3
  • MW: 197.38
  • EINECS:205-796-5
  • MDL Number:MFCD00009602
  • Synonyms:1,1,1-Trifluoro-2-bromo-2-chloroethane;1,1,1-Trifluoro-2-chloro-2-bromoethane;HALOTHANE;2-BROMO-2-CHLORO-1,1,1-TRIFLUOROETHANE;1-BROMO-1-CHLORO-2,2,2-TRIFLUOROETHANE;Halothane (1 mL);2-Bromo-1,1,1-trifluoroethane-2-chloro-;2-Bromo-2-chloro-1,1,1-trifluoroethane, Halothane
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :-115.75°C
Boiling point :50.2 °C(lit.)
Density :1.872 g/mL at 25 °C(lit.)
vapor pressure :4.5 psi ( 20 °C)
refractive index :n20/D 1.369(lit.)
Flash point :49-50°C
storage temp. :2-8°C
solubility :Slightly soluble in water, miscible with anhydrous ethanol and with trichloroethylene.
form :Colorless liquid
color :Colorless to light yellow
Water Solubility :Soluble in water (8 mg/ml).
Sensitive :Light Sensitive
Merck :14,4603
BRN :1736947
Exposure limits :TLV-TWA 50 ppm (～400 mg/m3) (ACGIH).
CAS DataBase Reference :151-67-7(CAS DataBase Reference)
EPA Substance Registry System :Halothane (151-67-7)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P201 Obtain special instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

1-Bromo-1-chloro-2,2,2-trifluoroethane has been used in a study that combined molecular simulations with free energy simulations to study solvation of halothane in polarizable water and methanol. It is also used in a study to investigate the interaction of anesthetics with the Rho GTPase regulator Rho GDP dissociation inhibitor. In an effect believed to be independent of anesthesia, halothane inhibits synthesis of 5-hydroxytryptamine in brain tissue, probably at the tryptophan hydroxylase step.

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Suppliers and manufacturers

CHEMSWORTH Pharmaffiliates Analytics and Synthetics P. Ltd Ion Bio Medi Care Private Limited Shirisha Enterprises Troikaa pharma Worldprime Export LLP Shree Sai Healthcare Indo Danish Laboratories Sanivex Healthcare Private Limited CLEARSYNTH LABS LTD.