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ChemicalBook > Product Catalogue >Biochemical Engineering >Plant extracts >Hinokitiol

Hinokitiol

Hinokitiol Structure
  • ₹2400 - ₹9937.35
  • Product name: Hinokitiol
  • CAS: 499-44-5
  • MF: C10H12O2
  • MW: 164.2
  • EINECS:207-880-7
  • MDL Number:MFCD00040180
  • Synonyms:HINOKITIOL;B-THUJAPLICIN;2-HYDROXY-4-ISOPROPYL-2,4,6-CYCLOHEPTATRIEN-1-ONE;2-hydroxy-6-isopropyl-cyclohepta-2,4,6-trien-1-one;2-hydroxy-6-propan-2-yl-cyclohepta-2,4,6-trien-1-one;2-hydroxy-6-propan-2-ylcyclohepta-2,4,6-trien-1-one;THUJAPLICIN, BETA- (RG);2-Hydroxy-4-isopropylcyclohepta-2,4,6-trien-1-one beta-Thujaplicine
Price3 Properties Safety Information Description
3 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)
  • TCI Chemicals (India)

Package

  • 1G
  • 5G
  • ManufacturerSigma-Aldrich(India)
  • Product number469521
  • Product descriptionβ-Thujaplicin 99%
  • Packaging5G
  • Price₹9937.35
  • Updated2022-06-14
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberH0142
  • Product descriptionHinokitiol min. 99.0 %
  • Packaging5G
  • Price₹7300
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberH0142
  • Product descriptionHinokitiol min. 99.0 %
  • Packaging1G
  • Price₹2400
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 469521 β-Thujaplicin 99% 5G ₹9937.35 2022-06-14 Buy
TCI Chemicals (India) H0142 Hinokitiol min. 99.0 % 5G ₹7300 2022-05-26 Buy
TCI Chemicals (India) H0142 Hinokitiol min. 99.0 % 1G ₹2400 2022-05-26 Buy

Properties

Melting point :50-52 °C(lit.)
Boiling point :140 °C10 mm Hg(lit.)
Density :1.0041 (rough estimate)
refractive index :1.5190 (estimate)
storage temp. :Sealed in dry,Room Temperature
solubility :Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
form :solid
pka :7.06±0.30(Predicted)
color :White
Odor :at 100.00 %. phenolic woody mossy
Odor Type :woody
Merck :14,9390
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 4 months.
LogP :1.137 (est)
CAS DataBase Reference :499-44-5(CAS DataBase Reference)
NIST Chemistry Reference :2,4,6-Cycloheptatrien-1-one, 2-hydroxy-4-(1-methylethyl)-(499-44-5)
EPA Substance Registry System :2,4,6-Cycloheptatrien-1-one, 2-hydroxy-4-(1-methylethyl)- (499-44-5)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P262 Do not get in eyes, on skin, or on clothing.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P284 Wear respiratory protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P391 Collect spillage. Hazardous to the aquatic environment
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Hinokitol, an iron chelator originally extracted from woods of Thuja plicata and Chamaecyparis obtuse, has been found to inhibit ultraviolet B-induced apoptosis in keratinocytes of murine ear skin via antioxidant activity of metallothionein. Additionally, this compound has been found to also cause apoptotic cell death and cell cycle arrest of proliferating F9 cells via iron deprivation, resulting in an arrest at the G1-S interface or S phase. Antimicrobial activity has also been displayed by Hinokitiol through CPA (carboxypeptidase A) inhibition. Other studies have reported Hinokitiol to inhibit melanin synthesis by reducing protein levels of microphthalmia-associated transcription factor (MITF) and of Tyrosinase, a rate limiting melanogenic enzyme. Hinokitiol is an inhibitor of 12-LO.

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Suppliers and manufacturers

Shaanxi Dideu Medichem Co. Ltd
Hinokitiol
₹20.00 /100KG
Hinokitiol CAS:499-44-5
Musks & Fragrance TCI Chemicals (India) Pvt. Ltd. A.J Chemicals CLEARSYNTH LABS LTD. Kowa India Pvt., Ltd. Akshaya Laboratories Pvt. Ltd Kowa India Private Limited
Shandong Natural Micron Pharm Tech Co.,LTD
Xi'an MC Biotech, Co., Ltd.