Ibandronic acid
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- ₹0
- Product name: Ibandronic acid
- CAS: 114084-78-5
- MF: C9H23NO7P2
- MW: 319.23
- EINECS:
- MDL Number:MFCD00868772
- Synonyms:{1-Hydroxy-3-(methylpentylamino)propylidene]bisphosphnic Acid;[1-Hydroxy-3-(methyl-d3-pentylamino)propylidene]bisphosphnic Acid;IBANDRONIC ACID-D3;1-Hydroxy-3-(methylpentylamino)propylidene bisphosphonic acid;Ibandronic acid;P,P'-[1-Hydroxy-3-(methylpentylamino)propylidene]bisphosphonic Acid;Ibadronic Acid;Ibandronate Acid
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Properties
Melting point :113-115°C
Boiling point :587.8±60.0 °C(Predicted)
Density :1.449±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :Aqueous Base (Slightly), Methanol (Slightly), Water (Slightly)
pka :1.60±0.10(Predicted)
form :Solid
color :White to Off-White
Stability :Hygroscopic
CAS DataBase Reference :114084-78-5(CAS DataBase Reference)
EPA Substance Registry System :Phosphonic acid, P,P'-[1-hydroxy-3-(methylpentylamino)propylidene]bis- (114084-78-5)
Boiling point :587.8±60.0 °C(Predicted)
Density :1.449±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :Aqueous Base (Slightly), Methanol (Slightly), Water (Slightly)
pka :1.60±0.10(Predicted)
form :Solid
color :White to Off-White
Stability :Hygroscopic
CAS DataBase Reference :114084-78-5(CAS DataBase Reference)
EPA Substance Registry System :Phosphonic acid, P,P'-[1-hydroxy-3-(methylpentylamino)propylidene]bis- (114084-78-5)
Safety Information
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Description
This third generation biphosphonate was launched in Austria and Germany for the treatment of bone disorders such as hypercalcemia in malignancy and ostedysis, Paget's disease and osteoporosis. It does not effect bone mineralization, therefore, the potential risk of osteomalacia is prevented. This was a problem with first generation derivatives. While the exact mode of action is not understood, they are inhibitors of osteroclast mediated bone resorption. These compounds strongly interact with hydroxyapatite crystals and have a half-life in the skeleton of several years. Despite this observation ibandronate was well tolerated and safe.More related product prices
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