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ChemicalBook > Product Catalogue >Organic Chemistry >Phosphines >Zoledronic acid

Zoledronic acid

Zoledronic acid Structure
  • ₹0
  • Product name: Zoledronic acid
  • CAS: 118072-93-8
  • MF: C5H10N2O7P2
  • MW: 272.09
  • EINECS:1806241-263-5
  • MDL Number:MFCD00867791
  • Synonyms:2-(imidazole-1-yl)-1-acetic acid HCl;CGP-42446;sMall aMount;Aclasta;BPH 91;Orazol;ZOL 446;1-HYDROXY-2-IMIDAZOLE-1-YLETHYLIDENE DIPHOSPHONIC ACID
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :193-2040C (dec)
Boiling point :764.0±70.0 °C(Predicted)
Density :2.13±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :Soluble in Water (up to 2 mg/ml).
form :solid
pka :1.41±0.10(Predicted)
color :White or off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 2 months.
CAS DataBase Reference :118072-93-8(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P272 Contaminated work clothing should not be allowed out of the workplace.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P333+P313 IF SKIN irritation or rash occurs: Get medical advice/attention.
P363 Wash contaminated clothing before reuse.
P501 Dispose of contents/container to..…

Description

Zoledronic acid is a white, crystalline powder that is available in vials for reconstitution for IV infusion over at least 15 minutes. It does not undergo metabolic transformation and does not inhibit CYP450 enzymes. Clearance of this agent is dependent on the patient's creatinine clearance, not on dose. Serum creatinine levels should be evaluated before every treatment. Zolendronic acid is contraindicated in patients with severe renal impairment.

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