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ChemicalBook > Product Catalogue >Pharmaceutical intermediates >Heterocyclic compound >Isoxazole

Isoxazole

Isoxazole Structure
  • ₹1102 - ₹9136.3
  • Product name: Isoxazole
  • CAS: 288-14-2
  • MF: C3H3NO
  • MW: 69.06
  • EINECS:206-018-7
  • MDL Number:MFCD00003149
  • Synonyms:ISOXAZOLE 98+%;1,2-Oxazole;Isoxazole,99%;Different oxazole;Isoxazole 99%;ISOXAZOLE;1-Oxa-2-azacyclopentadiene;Isooxazole
4 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)
  • ALFA India

Package

  • 5G
  • 25G
  • ManufacturerTCI Chemicals (India)
  • Product numberI0372
  • Product descriptionIsoxazole min. 95.0 %
  • Packaging5G
  • Price₹4000
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number151637
  • Product descriptionIsoxazole 99%
  • Packaging5G
  • Price₹2208.3
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number151637
  • Product descriptionIsoxazole 99%
  • Packaging25G
  • Price₹9136.3
  • Updated2022-06-14
  • Buy
  • ManufacturerALFA India
  • Product numberALF-L01607-06
  • Product descriptionIsoxazole, 99%
  • Packaging5g
  • Price₹1102
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) I0372 Isoxazole min. 95.0 % 5G ₹4000 2022-05-26 Buy
Sigma-Aldrich(India) 151637 Isoxazole 99% 5G ₹2208.3 2022-06-14 Buy
Sigma-Aldrich(India) 151637 Isoxazole 99% 25G ₹9136.3 2022-06-14 Buy
ALFA India ALF-L01607-06 Isoxazole, 99% 5g ₹1102 2022-05-26 Buy

Properties

Melting point :-67.1°C
Boiling point :93-95 °C(lit.)
Density :1.078 g/mL at 25 °C(lit.)
vapor density :2.4 (vs air)
refractive index :n20/D 1.427(lit.)
Flash point :48 °F
storage temp. :2-8°C
solubility :167g/l
pka :-2.0(at 25℃)
form :clear liquid
color :Colorless to Light yellow
BRN :103773
InChIKey :CTAPFRYPJLPFDF-UHFFFAOYSA-N
CAS DataBase Reference :288-14-2(CAS DataBase Reference)
NIST Chemistry Reference :Isoxazole(288-14-2)
EPA Substance Registry System :Isoxazole (288-14-2)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

Description

As an important class of heterocycles, isoxazole is a five membered heterocyclic compound with various pharmacological actions, which is found in some natural products, such as ibotenic acid. It is used in the formation of the basis for a number of drugs, such as the COX-2 inhibitor valdecoxib and anti-inflammatory drugs. Isoxazoles are largely applied in the area of pharmaceuticals and therapeutics, including insecticidal, antibacterial, antibiotic, antitumour, antifungal, antituberculosis, anticancer and ulcerogenic. Besides, it has a great effect on reducing blood glucose, eliminating pain, resisting inflammation, killing harmful bacteria, controlling and reducing the risk of HIV.
The isoxazole ring is an essential pharmacophore in modern drug discovery. Some beta-lactamase-resistant antibiotics contain an isoxazole group, including cloxacillin, dicloxacillin, flucloxacillin, and the isoxazole group is also found in some steroid drug such as danazol.

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