Ivabradine hydrochloride
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- ₹9645.08 - ₹37530.28
- Product name: Ivabradine hydrochloride
- CAS: 148849-67-6
- MF: C27H37ClN2O5
- MW: 505.05
- EINECS:638-798-3
- MDL Number:MFCD00929899
- Synonyms:Ivabradine hydrochloride;3-[3-[[(8S)-3,4-Dimethoxy-8-bicyclo[4.2.0]octa-1,3,5-trienyl]methyl-methylamino]propyl]-7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-one hydrochloride;Ivabradine hydrochloride, >=99%;IVABRADINE HYDROCHLORIDE-OTHER COMPOUNDSCONTAINING AN UNFUSED PYRAZOLE RING(WHETHER OR NOT HYDROGENATED)IN THE STRUCTUR;3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one Hydrochloride;Corlentor;S-16257;(7,8-Dimethoxy 3-(3-(((1S)-(4,5-dimethoxybenzocyclobutan-1-yl)methyl)methylamino)propyl)-1,3,4,5-tetrahydro-2H-benzazepin-2-one hydrochloride
4 prices
Selected condition:
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 10MG
- 50MG
- 200MG
- 1G
- ManufacturerTCI Chemicals (India)
- Product numberI0847
- Product descriptionIvabradine Hydrochloride
- Packaging200MG
- Price₹9700
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberI0847
- Product descriptionIvabradine Hydrochloride
- Packaging1G
- Price₹25500
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML0281
- Product descriptionIvabradine hydrochloride ≥98% (HPLC)
- Packaging10MG
- Price₹9645.08
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML0281
- Product descriptionIvabradine hydrochloride ≥98% (HPLC)
- Packaging50MG
- Price₹37530.28
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
TCI Chemicals (India) | I0847 | Ivabradine Hydrochloride | 200MG | ₹9700 | 2022-05-26 | Buy |
TCI Chemicals (India) | I0847 | Ivabradine Hydrochloride | 1G | ₹25500 | 2022-05-26 | Buy |
Sigma-Aldrich(India) | SML0281 | Ivabradine hydrochloride ≥98% (HPLC) | 10MG | ₹9645.08 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | SML0281 | Ivabradine hydrochloride ≥98% (HPLC) | 50MG | ₹37530.28 | 2022-06-14 | Buy |
Properties
Melting point :193-196?C
alpha :58921 +7.8°; 36521 +27.8° (c = 1% in DMSO)
storage temp. :2-8°C
solubility :H2O: ≥5mg/mL (warmed)
form :powder
color :white to beige
optical activity :[α]/D +5 to +9°, c = 1 in DMSO
Merck :14,5247
InChIKey :HLUKNZUABFFNQS-ZMBIFBSDSA-N
SMILES :C([C@H]1CC2=CC(OC)=C(OC)C=C12)N(C)CCCN1CCC2=CC(OC)=C(OC)C=C2CC1=O.Cl |&1:1,r|
CAS DataBase Reference :148849-67-6(CAS DataBase Reference)
alpha :58921 +7.8°; 36521 +27.8° (c = 1% in DMSO)
storage temp. :2-8°C
solubility :H2O: ≥5mg/mL (warmed)
form :powder
color :white to beige
optical activity :[α]/D +5 to +9°, c = 1 in DMSO
Merck :14,5247
InChIKey :HLUKNZUABFFNQS-ZMBIFBSDSA-N
SMILES :C([C@H]1CC2=CC(OC)=C(OC)C=C12)N(C)CCCN1CCC2=CC(OC)=C(OC)C=C2CC1=O.Cl |&1:1,r|
CAS DataBase Reference :148849-67-6(CAS DataBase Reference)
Safety Information
Symbol(GHS): |
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Signal word: | Warning | ||||||||||||||
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Description
Ivabradine is a highly selective open channel blocker that targets the mixed Na+/K+ inward “funny current” (If) carried by hyperpolarization-activated cyclic nucleotide gated (HCN) channels. It suppresses channel activity at HCN1, HCN2, and HCN4, all with the same EC50 value of 4 μM. Notably, ivabradine selectively targets cardiac signaling, resulting in resting heart rate reducing (bradycardic) effects.More related product prices
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