KNK437
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- ₹11528.63 - ₹46515.03
- Product name: KNK437
- CAS: 218924-25-5
- MF: C13H11NO4
- MW: 245.23
- EINECS:
- MDL Number:MFCD24369049
- Synonyms:N-FORMYL-3,4-METHYLENEDIOXY-BENZYLIDINE-GAMMA-BUTYROLACTAM;3,4-METHYLENEDIOXY-BENZYLIDINE-GAMMA-BUTYROLACTAM;KNK423;KNK437;HEAT SHOCK PROTEIN INHIBITOR I;HEAT SHOCK PROTEIN INHIBITOR II;3-(1,3-Benzodioxol-5-ylmethylene)-2-oxo-1-pyrrolidinecarboxaldehyde;Heat Shock Protein Inhibitor I - CAS 218924-25-5 - Calbiochem
3 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberSML0964
- Product descriptionKNK437 ≥98% (HPLC)
- Packaging5MG
- Price₹11528.63
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number373260
- Product descriptionHeat Shock Protein Inhibitor I - CAS 218924-25-5 - Calbiochem Heat Shock Protein Inhibitor I, CAS 218924-25-5 blocks the induction of HSP70, HSP72, and HSP105. Blocks the development of thermotolerance in a dose-
- Packaging5MG
- Price₹24680
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML0964
- Product descriptionKNK437 ≥98% (HPLC)
- Packaging25MG
- Price₹46515.03
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | SML0964 | KNK437 ≥98% (HPLC) | 5MG | ₹11528.63 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 373260 | Heat Shock Protein Inhibitor I - CAS 218924-25-5 - Calbiochem Heat Shock Protein Inhibitor I, CAS 218924-25-5 blocks the induction of HSP70, HSP72, and HSP105. Blocks the development of thermotolerance in a dose- | 5MG | ₹24680 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SML0964 | KNK437 ≥98% (HPLC) | 25MG | ₹46515.03 | 2022-06-14 | Buy |
Properties
Boiling point :412.4±55.0 °C(Predicted)
Density :1.515±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: soluble5mg/mL, clear (warmed)
form :White to light yellow powder
pka :-1.70±0.20(Predicted)
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Density :1.515±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: soluble5mg/mL, clear (warmed)
form :White to light yellow powder
pka :-1.70±0.20(Predicted)
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety Information
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Description
Heat shock protein (Hsp) inhibitor I is a benzylidene lactam compound that prevents the synthesis of inducible Hsps Hsp105, Hsp72, and Hsp40. At 100 μM, it can inhibit the development of thermotolerance in COLO 320 DM cells. Its effects on thermotolerance have been studied in the context of clinical fractionated hyperthermia as a modality of cancer therapy.Related product price
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