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L-Thyroxine-13C9,15N

L-Thyroxine-13C9,15N Structure
  • ₹0
  • Product name: L-Thyroxine-13C9,15N
  • CAS: 1431868-11-9
  • MF: C15H11I4NO4
  • MW: 786.96002
  • EINECS:
  • MDL Number:
  • Synonyms:L-Thyroxine-13C9,15N;Levothyroxine-13C9-15N;Thyroxine Carboxy,α,β,1,2,3,4,5,6-13C9,15N;O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine-carboxy,α,β,1,2,3,4,5,6-13C9-15N
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Properties

storage temp. :Store at -20°C
solubility :DMF: 0.14 mg/ml; DMSO: 2.5 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.50 mg/ml
form :A solid

Safety Information

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Description

L-Thyroxine-13C9,15N is intended for use as an internal standard for the quantification of L-thyroxine by GC- or LC-MS. L-Thyroxine is a synthetic form of the thyroid hormone thyroxine. In vivo, L-thyroxine (0.9 and 2.7 μg) inhibits synthesis and release of thyrotropin induced by thyrotropin-releasing hormone from the anterior pituitary in mice. It also reverses decreases in levels of circulating thymic serum factor (FTS) and the number of T rosette-forming cells in an old age-induced mouse model of hypothyroidism. Formulations containing L-thyroxine have been used in the treatment of hypothyroidism.

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