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ChemicalBook > Product Catalogue >API >Drug metabolism >3,3',5-Triiodo-L-thyronine

3,3',5-Triiodo-L-thyronine

3,3',5-Triiodo-L-thyronine Structure
  • ₹4500 - ₹131826.85
  • Product name: 3,3',5-Triiodo-L-thyronine
  • CAS: 6893-02-3
  • MF: C15H12I3NO4
  • MW: 650.97
  • EINECS:229-999-3
  • MDL Number:MFCD00002593
  • Synonyms:L-Tyrosine, O-(4-hydroxy-3-iodophenyl)-3,5-diiodo- (9CI);NSC 80203;Thyronine, 3,3',5-triiodo-, L- (6CI);IODOTHYRONINE;3,3,5-TRIIODO-L -THYRONINE 95-98% FREE ACID CRYSTALLINE;3,3μ,5 Triiodothyronine (T3);3,3μ,5-Triiodo-L-thyronine, Liothyronine, T3, O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine;Liothyronine, T3, O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine
10 prices
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)
  • SRL

Package

  • 100MG
  • 250MG
  • 500MG
  • 1G
  • 1ML
  • 5G
  • 1Gms
  • ManufacturerTCI Chemicals (India)
  • Product numberT0453
  • Product description3,3',5-Triiodo-L-thyronine
  • Packaging100MG
  • Price₹4500
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT2877
  • Product description3,3′,5-Triiodo-L-thyronine ≥95% (HPLC), powder
  • Packaging100MG
  • Price₹6246.03
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT-074
  • Product description3,3′,5-Triiodo-L-thyronine (T3) solution 100?μg/mL in methanol with 0.1N NH3, ampule of 1?mL, certified reference material, Cerilliant?
  • Packaging1ML
  • Price₹9921.8
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT2877
  • Product description3,3′,5-Triiodo-L-thyronine ≥95% (HPLC), powder
  • Packaging250MG
  • Price₹13585.38
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1504
  • Product descriptionLiothyronine Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging500MG
  • Price₹15014.28
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT2877
  • Product description3,3′,5-Triiodo-L-thyronine ≥95% (HPLC), powder
  • Packaging500MG
  • Price₹20296.88
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT2877
  • Product description3,3′,5-Triiodo-L-thyronine ≥95% (HPLC), powder
  • Packaging1G
  • Price₹30667.23
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT2877
  • Product description3,3′,5-Triiodo-L-thyronine ≥95% (HPLC), powder
  • Packaging5G
  • Price₹131826.85
  • Updated2022-06-14
  • Buy
  • ManufacturerSRL
  • Product number35241
  • Product description3,3,5-Triiodo-L-Thyronine extrapure, 95%
  • Packaging1Gms
  • Price₹28430
  • Updated2022-05-26
  • Buy
  • ManufacturerSRL
  • Product number35241
  • Product description3,3,5-Triiodo-L-Thyronine extrapure, 95%
  • Packaging100mg
  • Price₹4700
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) T0453 3,3',5-Triiodo-L-thyronine 100MG ₹4500 2022-05-26 Buy
Sigma-Aldrich(India) T2877 3,3′,5-Triiodo-L-thyronine ≥95% (HPLC), powder 100MG ₹6246.03 2022-06-14 Buy
Sigma-Aldrich(India) T-074 3,3′,5-Triiodo-L-thyronine (T3) solution 100?μg/mL in methanol with 0.1N NH3, ampule of 1?mL, certified reference material, Cerilliant? 1ML ₹9921.8 2022-06-14 Buy
Sigma-Aldrich(India) T2877 3,3′,5-Triiodo-L-thyronine ≥95% (HPLC), powder 250MG ₹13585.38 2022-06-14 Buy
Sigma-Aldrich(India) PHR1504 Liothyronine Pharmaceutical Secondary Standard; Certified Reference Material 500MG ₹15014.28 2022-06-14 Buy
Sigma-Aldrich(India) T2877 3,3′,5-Triiodo-L-thyronine ≥95% (HPLC), powder 500MG ₹20296.88 2022-06-14 Buy
Sigma-Aldrich(India) T2877 3,3′,5-Triiodo-L-thyronine ≥95% (HPLC), powder 1G ₹30667.23 2022-06-14 Buy
Sigma-Aldrich(India) T2877 3,3′,5-Triiodo-L-thyronine ≥95% (HPLC), powder 5G ₹131826.85 2022-06-14 Buy
SRL 35241 3,3,5-Triiodo-L-Thyronine extrapure, 95% 1Gms ₹28430 2022-05-26 Buy
SRL 35241 3,3,5-Triiodo-L-Thyronine extrapure, 95% 100mg ₹4700 2022-05-26 Buy

Properties

Melting point :234-238 °C(lit.)
alpha :23 º (c=2 in ethanol)
Boiling point :232°C (rough estimate)
Density :2.2155 (estimate)
Flash point :9°C
storage temp. :-20°C
solubility :DMSO (Slightly), Methanol (Very Slightly)
form :powder
pka :pKa 8.5 (Uncertain);8.4 (Uncertain);8.45 (Uncertain)
color :Off-white to pale yellow
optical activity :[α]25/D +23.0°, c = 2 in 1 N HCl: ethanol, 1:2
Water Solubility :Insoluble in water, ethanol and propylene glycol. Soluble in dilute alkalies.
Sensitive :Light Sensitive
Merck :14,5510
BRN :2710227
Stability :Light Sensitive
CAS DataBase Reference :6893-02-3(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Description

Using video intensification fluorescence microscopy and tetramethylrhodamine (Rho)-labeled 3, 3', 5-triiodo-L-thyronine (T3),the uptake of T3 by cultured mouse fibroblasts was studied. The binding of 3, 3', 5-triiodo-L-thyronine (T3) to GH3 rat pituitary tumor cells was studied at 15 degrees C and was shown to be saturable, reversible, and stereospecific. A fluorescent derivative of the thyroid hormone 3,3'-triiodo-L-thyronine binds to cultured mouse fibroblasts; such binding is saturable. 3,3?,5-Triiodo-L-thyronine Up-regulation of Na,K-ATPase Activity and Cell Surface Expression in Alveolar Epithelial Cells Is Src Kinase- and Phosphoinositide 3-Kinase-dependent.

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