LFM-A13
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- ₹12849.28
- Product name: LFM-A13
- CAS: 244240-24-2
- MF: C11H8Br2N2O2
- MW: 360
- EINECS:
- MDL Number:MFCD09878279
- Synonyms:α-cyano-β-hydroxy-β-methyl-n-(2,5-dibromophenyl)propenamide;(Z)-2-cyano-N-(2,5-dibroMophenyl)-3-hydroxybut-2-enaMide(LFM-A13);(Z)-2-cyano-N-(2,5-dibromophenyl)-3-hydroxybut-2-enamide;(2Z)-2-Cyano-N-(2,5-dibromophenyl)-3-hydroxy-2-butenamide;a-Cyano-b-hydroxy-b-methyl-N-(2,5-dibromophenyl)propenamide;2-cyano-N-(2,5-dibromophenyl) -3-oxobutanamide;LFM-A13(Z);2-Butenamide,2-cyano-N-(2,5-dibromophenyl)-3-hydroxy-, (2Z)-
1 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- ManufacturerSigma-Aldrich(India)
- Product numberL6920
- Product descriptionLFM-A13 ≥98% (HPLC), powder
- Packaging5MG
- Price₹12849.28
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | L6920 | LFM-A13 ≥98% (HPLC), powder | 5MG | ₹12849.28 | 2022-06-14 | Buy |
Properties
Melting point :150-151 °C
Boiling point :487.9±45.0 °C(Predicted)
Density :1.909±0.06 g/cm3(Predicted)
storage temp. :−20°C
solubility :DMSO: 15 mg/mL
form :powder
pka :5.20±0.50(Predicted)
color :white
Stability :Stable for 2 years from date of purchase as supplied. PROTECT FROM MOISTURE. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Boiling point :487.9±45.0 °C(Predicted)
Density :1.909±0.06 g/cm3(Predicted)
storage temp. :−20°C
solubility :DMSO: 15 mg/mL
form :powder
pka :5.20±0.50(Predicted)
color :white
Stability :Stable for 2 years from date of purchase as supplied. PROTECT FROM MOISTURE. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Safety Information
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| Signal word: | Warning | ||||||||||
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Description
LFM-A13 (244240-24-2) is a selective inhibitor of Bruton’s tyrosine kinase (BTK) – IC50‘s = 2.5 μM (recombinant BTK) and 17.2 μM (human BTK).1,2 It has also been shown to inhibit Polo-like kinase (PLK) – IC50 = 61 μM for human PLK3.3 LFM-A13 displayed no activity (concentrations up to 278 μM) at JAK1, JAK3, HCK, EGFRK and IRK2 or CDK1-3, CHK1, IKK, MAPK1, SAPK2a and ten other tyrosine kinases.3Related product price
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