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ChemicalBook > Product Catalogue >API >Antiparasitic drugs >Anthelmintics >Levamisole

Levamisole

Levamisole Structure
  • ₹0
  • Product name: Levamisole
  • CAS: 14769-73-4
  • MF: C11H12N2S
  • MW: 204.29
  • EINECS:238-836-5
  • MDL Number:MFCD00066738
  • Synonyms:L-6-PHENYL-2,3,5,6-TETRAHYDROIMIDAZOL(2,1-B) THIAZOLE;IMMUNOPURE(R) PHOSPHATASE SUPPRESSOR;LEVAMISOLE;(s)-2,3,5,6-tetrahydro-6-phenylimidazo[2,1-b]thiazole;l-tetramisole;6-PHENYL-2,3,5,6-TETRAHYDROIMIDAZO[2,1-B]THIAZOLE (LEVAMISOLE);(6S)-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole;Ketrax
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :60-61.5°
alpha :D25 -85.1° (c = 10 in chloroform)
Boiling point :344.4±45.0 °C(Predicted)
Density :1.32±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :Chloroform (Slightly), Methanol (Slightly)
form :Solid
pka :10.00±0.40(Predicted)
color :Off-White to Pale Yellow
InChI :InChI=1S/C11H12N2S/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10/h1-5,10H,6-8H2/t10-/m1/s1
InChIKey :HLFSDGLLUJUHTE-SNVBAGLBSA-N
SMILES :S1CCN2C[C@H](C3=CC=CC=C3)N=C12
CAS DataBase Reference :14769-73-4(CAS DataBase Reference)
EPA Substance Registry System :Levamisole (14769-73-4)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P330 Rinse mouth.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.

Description

Levamisole (Ergamisol) is an antiparasitic drug that has been found to enhance T-cell function and cellular immunity. The drug improves survival of patients with resected colorectal cancers when combined with 5-fluorouracil; the mechanism of this interaction is not known. Levamisole does not have antitumor activity against established or metastatic cancer and has not been found useful in the adjuvant therapy of cancers other than colorectal cancer.

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