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ChemicalBook > Product Catalogue >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >Lexithromycin

Lexithromycin

Lexithromycin Structure
  • ₹0
  • Product name: Lexithromycin
  • CAS: 53066-26-5
  • MF: C38H70N2O13
  • MW: 762.97
  • EINECS:
  • MDL Number:
  • Synonyms:erythromycin A methoxime;9-(Methoxyimino)-9-deoxoerythromycin;9-Deoxo-9-[[methyloxy]imino]erythromycin;ErythroMycin A 9-MethoxiMe, Wy 48314;Erythromycin A-E-oxime;Erythromycin A-E-oxime LEXITHROMYCIN.;Lexithromycin;Erythromycin A 9-Methoxime
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Properties

Melting point :>115°C (dec.)
Boiling point :824.6±75.0 °C(Predicted)
Density :1.26±0.1 g/cm3(Predicted)
storage temp. :Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility :Chloroform (Slightly), DMSO (Slightly)
pka :13.19±0.70(Predicted)
form :Solid
color :White to Off-White
Stability :Hygroscopic

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Lexithromycin is a semisynthetic antibiotic derived from erythromycin . Lexithromycin has improved absorption in vivo over erythromycin due to increased hydrophopicity and pH stability. As with other macrolides, lexithromycin prevents protein synthesis by binding the ribosome at the polypeptide exit tunnel. Formulations containing lexithromycin were tested in clinical trials as treatment for HIV but were discontinued.

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