Lometrexol
- ₹26184.9 - ₹115007.1
- Product name: Lometrexol
- CAS: 106400-81-1
- MF: C21H25N5O6
- MW: 443.45
- EINECS:
- MDL Number:
- Synonyms:Lometrexol;(6R)-5,10-Dideaza-5,6,7,8-tetrahydrofolic acid;N-[4-[2-[[(6R)-2-Amino-3,4,5,6,7,8-hexahydro-4-oxopyrido[2,3-d]pyrimidin]-6-yl]ethyl]benzoyl]-L-glutamic acid;N-[4-[2-[[(R)-2-Amino-4-oxo-1,4,5,6,7,8-hexahydropyrido[2,3-d]pyrimidin]-6-yl]ethyl]benzoyl]-L-glutamic acid;L-Glutamic acid, N-(4-(2-((6R)-2-amino-1,4,5,6,7,8-hexahydro-4-oxopyrido(2,3-D)pyrimidin-6-yl)ethyl)benzoyl)-;L-Glutamic acid, N-(4-(2-(2-amino-1,4,5,6,7,8-hexahydro-4-oxopyrido(2,3-D)pyrimidin-6-yl)ethyl)benzoyl)-, (R)-;Lometrexolum;Lometrexolum [inn-latin]
2 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberSML0040
- Product descriptionLometrexol hydrate ≥95% (HPLC)
- Packaging5MG
- Price₹26184.9
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML0040
- Product descriptionLometrexol hydrate ≥95% (HPLC)
- Packaging25MG
- Price₹115007.1
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | SML0040 | Lometrexol hydrate ≥95% (HPLC) | 5MG | ₹26184.9 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | SML0040 | Lometrexol hydrate ≥95% (HPLC) | 25MG | ₹115007.1 | 2022-06-14 | Buy |
Properties
Density :1.56±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥5mg/mL
pka :3.60±0.10(Predicted)
form :powder
color :white to light yellow
Stability :Hygroscopic
storage temp. :2-8°C
solubility :DMSO: ≥5mg/mL
pka :3.60±0.10(Predicted)
form :powder
color :white to light yellow
Stability :Hygroscopic
Safety Information
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Signal word: | Danger | ||||||||||||||
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Description
Glycinamide ribonucleotide formyltransferase (GART) is a folate-dependent enzyme required for de novo purine synthesis. Lometrexol is a folate analog antimetabolite with antineoplastic activity. At nanomolar conentrations, it inhibits GART preventing de novo purine synthesis, inhibiting DNA synthesis, arresting cells in the S phase of the cell cycle, and inhibiting tumor cell proliferation.Related product price
- 2,4-Diamino-6-hydroxypyrimidine
₹1492-18099 - Lometrexol
₹26184.9-115007.1 - TETRAHYDROFOLIC ACID
₹7328.53-83428.28