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ChemicalBook > Product Catalogue >API >Circulatory system drugs >Antihypertensive drugs >Losartan

Losartan

Losartan Structure
  • ₹0
  • Product name: Losartan
  • CAS: 114798-26-4
  • MF: C22H23ClN6O
  • MW: 422.91
  • EINECS:601-329-8
  • MDL Number:MFCD00865831
  • Synonyms:2-Butyl-4-chloro-5-(hydroxymethyl)-1-[(2'-(1H-tetrazol-5-yl)-1,1'-biphenyl-4-yl)methyl]-1H-imidazole;Compound 89;2-n-butyl-4-chloro-5-hydroxyMethyl-1-[(2'-(1H-tetrazole-5-yl)biph;2-Butyl-4-chloro-1-[[2'-(2H-tetrazol-5-yl)-biphenyl-4-yl]methyl]-1H-imidazol-5-methanol;(2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazol-5-yl)methanol;dup89 ;nyl)-4-yl)methyl)- ;2-butyl-4-chloro-1-[p-(o-1h-tetrazol-5-ylphenyl)benzyl]imidazole-5- methanol
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :183-184 C
Boiling point :682.0±65.0 °C(Predicted)
Density :1.35±0.1 g/cm3(Predicted)
vapor pressure :0.002Pa at 20℃
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :5-6(at 25℃)
color :White to Off-White
Water Solubility :4.8mg/L at 20℃
LogP :1.1 at 20℃
CAS DataBase Reference :114798-26-4(CAS DataBase Reference)
EPA Substance Registry System :1H-Imidazole-5-methanol, 2-butyl-4-chloro-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]- (114798-26-4)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H362 May cause harm to breast-fed children Reproductive toxicity, effects on or via lactation Additional category P201, P260, P263, P264, P270,P308+P313
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P263 Avoid contact during pregnancy/while nursing.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Losartan is a nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive.

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