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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Epigenetics >HDAC inhibitors >MC1568

MC1568

MC1568 Structure
  • ₹21390.2 - ₹85301
  • Product name: MC1568
  • CAS: 852475-26-4
  • MF: C17H15FN2O3
  • MW: 314.31
  • EINECS:
  • MDL Number:MFCD16875423
  • Synonyms:3-[4-(3-(3-Fluorophenyl)-3-oxo-1-propen-1-yl)-1-Methyl-1H-pyrrol-2-yl]-N-hydroxy-2-propenaMide;(E)-3-(4-((E)-3-(3-fluorophenyl)-3-oxoprop-1-enyl)-1-methyl-1H-pyrrol-2-yl)-N-hydroxyacrylamide;3-[4-[3-(3-Fluorophenyl)-3-oxo-1-propenyl]-1-methyl-1H-pyrrol-2-yl]-N-hydroxy-2-propenamide MC1568;MC 1568 3-[4-[3-(3-Fluorophenyl)-3-oxo-1-propenyl]-1-methyl-1H-pyrrol-2-yl]-N-hydroxy-2-propenamide;(E)-3-(5-((E)-3-(3-fluorophenyl)-3-oxoprop-1-enyl)-1-methyl-1H-pyrrol-2-yl)-N-hydroxyacrylamide;3-[5-(3-(3-Fluorophenyl)-3-oxopropen-1-yl)-1-methyl-1H-pyrrol-2-yl]-N-hydroxy-2-propenamide;MC 1568, >=98%;(E)-3-(5-((E)-3-(3-fluorophenyl)-3-oxoprop-1-en-1-yl)-1-methyl-1H-pyrrol-2-yl)-N-hydroxyacrylamide
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberM1824
  • Product descriptionMC1568 ≥97% (HPLC)
  • Packaging5MG
  • Price₹21390.2
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberM1824
  • Product descriptionMC1568 ≥97% (HPLC)
  • Packaging25MG
  • Price₹85301
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) M1824 MC1568 ≥97% (HPLC) 5MG ₹21390.2 2022-06-14 Buy
Sigma-Aldrich(India) M1824 MC1568 ≥97% (HPLC) 25MG ₹85301 2022-06-14 Buy

Properties

Melting point :212-215 °C(Solv: acetonitrile (75-05-8); methanol (67-56-1))
Density :1.21±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥10mg/mL
form :powder
pka :8.91±0.23(Predicted)
color :orange
InChIKey :QRDAPCMJAOQZSU-KQQUZDAGSA-N
CAS DataBase Reference :852475-26-4

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

While class I HDACs are localized predominantly within the nucleus, class II HDACs shuttle into and out of the nucleus in response to intracellular signaling. Class IIa HDACs, which includes HDAC4, 5, 7, and 9, commonly act as corepressors and play diverse roles in cell biology. MC 1568 is a selective inhibitor of class IIa HDACs, with greater than 170-fold selectivity over class I HDACs, including HDAC1. It has been used in cells (1-10 μM) and in mice to elucidate the roles of class IIa HDACs in cell proliferation and differentiation, apoptosis, myogenesis, adipogenesis, and fibrosis.

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