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ChemicalBook > Product Catalogue >API >Nervous system drugs >Antidepressants, Antimanics drugs >Maprotiline hydrochloride

Maprotiline hydrochloride

Maprotiline hydrochloride Structure
  • ₹3790.5 - ₹27647.05
  • Product name: Maprotiline hydrochloride
  • CAS: 10347-81-6
  • MF: C20H24ClN
  • MW: 313.86
  • EINECS:233-758-8
  • MDL Number:MFCD00079464
  • Synonyms:10-ethanoanthracene-9(10h)-propylamine,n-methyl-hydrochloride ;ba34276 ;ciba34276ba ;ciba34276hydrochloride ;n-methyl-9,10-ethanoanthracene-9(10h)-propanaminehydrochloride ;9-[GAMMA-METHYLAMINOPROPYL]-9,10-DIHYDRO-9,10-ETHANOANTHRACENE HYDROCHLORIDE;1-(3-METHYLAMINOPROPYL)DIBENZO[B,E]BICYCLO[2.2.2]OCTADIENE HYDROCHLORIDE;MAPROTILENE HYDROCHLORIDE
6 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 500MG
  • 1ML
  • 1G
  • 5G
  • ManufacturerTCI Chemicals (India)
  • Product numberM2527
  • Product descriptionMaprotiline Hydrochloride
  • Packaging1G
  • Price₹7400
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberM2527
  • Product descriptionMaprotiline Hydrochloride
  • Packaging5G
  • Price₹19500
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberM-920
  • Product descriptionMaprotiline hydrochloride solution 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant?
  • Packaging1ML
  • Price₹3790.5
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberM9651
  • Product descriptionMaprotiline hydrochloride >99% (HPLC), powder
  • Packaging1G
  • Price₹8389.38
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR3033
  • Product descriptionMaprotiline Hydrochloride pharmaceutical secondary standard, certified reference material
  • Packaging500MG
  • Price₹15490.58
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberM9651
  • Product descriptionMaprotiline hydrochloride >99% (HPLC), powder
  • Packaging5G
  • Price₹27647.05
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) M2527 Maprotiline Hydrochloride 1G ₹7400 2022-05-26 Buy
TCI Chemicals (India) M2527 Maprotiline Hydrochloride 5G ₹19500 2022-05-26 Buy
Sigma-Aldrich(India) M-920 Maprotiline hydrochloride solution 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant? 1ML ₹3790.5 2022-06-14 Buy
Sigma-Aldrich(India) M9651 Maprotiline hydrochloride >99% (HPLC), powder 1G ₹8389.38 2022-06-14 Buy
Sigma-Aldrich(India) PHR3033 Maprotiline Hydrochloride pharmaceutical secondary standard, certified reference material 500MG ₹15490.58 2022-06-14 Buy
Sigma-Aldrich(India) M9651 Maprotiline hydrochloride >99% (HPLC), powder 5G ₹27647.05 2022-06-14 Buy

Properties

Melting point :230-232°C
Flash point :9℃
storage temp. :2-8°C
solubility :H2O: 50 mg/mL
form :powder
color :white
Water Solubility :Soluble to 50mg/ml in water. Soluble in ethanol at 10mM
Merck :14,5748

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:

Description

Maprotiline is a norepinephrine reuptake inhibitor that binds the norepinephrine transporter with a KD value of 11.1 nM. Comparatively, it only weakly associates with serotonin and dopamine transporters (KDs = 5.8 and 1 μM, respectively). However, maprotiline moderately inhibits serotonin 5-HT2A receptors with a Ki value of 51 nM. Maprotiline has also been reported to bind the histamine H1, muscarinic acetylcholine, α1-adrenergic, and dopamine D2 receptors with KD values of 2, 570, 90, and 350 nM, respectively. It has been used in the treatment of depression and also has been reported to possess sedative, anxiolytic, and sympathomimetic activities.

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