Melphalan
- ₹17937.03 - ₹91016.6
- Product name: Melphalan
- CAS: 148-82-3
- MF: C13H18Cl2N2O2
- MW: 305.2
- EINECS:205-726-3
- MDL Number:MFCD00057717
- Synonyms:L-PHENYL-ALANINE MUSTARD;L-PAM;at-290 ;cb3025 ;l-3-(p-(bis(2-chloroethyl)amino)phenyl)alanine ;l-3-(para-(bis(2-chloroethyl)amino)phenyl)alanine ;levofalan ;l-sarcolysin
3 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 100MG
- 250MG
- 1G
- ManufacturerSigma-Aldrich(India)
- Product numberM2011
- Product descriptionMelphalan powder
- Packaging100MG
- Price₹17937.03
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberM2011
- Product descriptionMelphalan powder
- Packaging250MG
- Price₹33405.95
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberM2011
- Product descriptionMelphalan powder
- Packaging1G
- Price₹91016.6
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | M2011 | Melphalan powder | 100MG | ₹17937.03 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | M2011 | Melphalan powder | 250MG | ₹33405.95 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | M2011 | Melphalan powder | 1G | ₹91016.6 | 2022-06-14 | Buy |
Properties
Melting point :~180 °C
Boiling point :473.1±45.0 °C(Predicted)
alpha :D25 +7.5° (c = 1.33 in 1.0N HCl); D22 -31.5° (c = 0.67 in methanol)
Density :1.3587 (rough estimate)
refractive index :1.6070 (estimate)
storage temp. :-20°C Freezer
solubility :95% ethanol and 1 drop 6 N HCl: 0.05 g/mL, clear
form :powder
pka :pKa 1.42/2.75/9.17(H2O,t =37.0,I=0.5) (Uncertain)
color :white
Water Solubility :<0.1 g/100 mL at 22 ºC
Merck :13,5850
BRN :2816456
InChIKey :SGDBTWWWUNNDEQ-LBPRGKRZSA-N
CAS DataBase Reference :148-82-3(CAS DataBase Reference)
IARC :1 (Vol. 9, Sup 7, 100A) 2012
EPA Substance Registry System :Melphalan (148-82-3)
Boiling point :473.1±45.0 °C(Predicted)
alpha :D25 +7.5° (c = 1.33 in 1.0N HCl); D22 -31.5° (c = 0.67 in methanol)
Density :1.3587 (rough estimate)
refractive index :1.6070 (estimate)
storage temp. :-20°C Freezer
solubility :95% ethanol and 1 drop 6 N HCl: 0.05 g/mL, clear
form :powder
pka :pKa 1.42/2.75/9.17(H2O,t =37.0,I=0.5) (Uncertain)
color :white
Water Solubility :<0.1 g/100 mL at 22 ºC
Merck :13,5850
BRN :2816456
InChIKey :SGDBTWWWUNNDEQ-LBPRGKRZSA-N
CAS DataBase Reference :148-82-3(CAS DataBase Reference)
IARC :1 (Vol. 9, Sup 7, 100A) 2012
EPA Substance Registry System :Melphalan (148-82-3)
Safety Information
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Description
Melphalan is a phenylalanine derivative of mechlorethamine, belonging to the family of nitrogen mustard alkylating agents that are used for chemotherapy. It attaches an alkyl group to guanine bases in DNA at the 7-nitrogen of the imidazole ring, which leads to DNA interstrand and intrastrand crosslinks, cytotoxicity, and apoptosis. Melphalan can inhibit the growth of PC-3 prostate cancer cells with IC50 values of 0.074 or 0.77 μM for sequential dosing or single dosing, respectively.Related product price
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