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ChemicalBook > Product Catalogue >API >Antibiotics >Tetracycline drugs >Minocycline

Minocycline

Minocycline Structure
  • ₹0
  • Product name: Minocycline
  • CAS: 10118-90-8
  • MF: C23H27N3O7
  • MW: 457.48
  • EINECS:800-277-5
  • MDL Number:MFCD00072105
  • Synonyms:7-DIMETHYLAMINO-6-DEMETHYL-6-DEOXYTETRACYCLINE HYDROCHLORIDE;7-DIMETHYLAMINO-6-DEMETHYL-6-DEOXYTETRACYCLINE, HCL;MYNOCINE;MINOCIN;MINOCYCLINE;MinocyclineBase;Minocycline Hcl 13614-98-7 / Base;2-Naphthacenecarboxamide, 4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo- (8CI)
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

alpha :D25 -166° (c = 0.524)
Boiling point :563.31°C (rough estimate)
Density :1.3283 (rough estimate)
refractive index :1.6500 (estimate)
solubility :Methanol (Slightly)
pka :pKa 2.8 (Uncertain);5.0 (Uncertain);7.8 (Uncertain);9.5 (Uncertain)
form :Solid
color :Yellow to Dark Orange
Water Solubility :52g/L(25 ºC)
Stability :Light Sensitive
CAS DataBase Reference :10118-90-8(CAS DataBase Reference)
EPA Substance Registry System :Minocycline (10118-90-8)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H362 May cause harm to breast-fed children Reproductive toxicity, effects on or via lactation Additional category P201, P260, P263, P264, P270,P308+P313
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P263 Avoid contact during pregnancy/while nursing.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P281 Use personal protective equipment as required.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

An important antibiotic produced by semisynthesis from demeclocycline is minocycline. It is much more lipophilic than its precursors, gives excellent blood levels following oral administration (90–100% available),and can be given once a day. Its absorption is lowered by approximately 20% when taken with food or milk. It is less dependent on active uptake mechanisms and has a somewhat broader antimicrobial spectrum. It also, apparently, is less painful on IM or IV injection, but it has vestibular toxicities (e.g., vertigo, ataxia, and nausea) not generally shared by other tetracyclines.

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Suppliers and manufacturers

Hebei Mojin Biotechnology Co., Ltd
Minocycline
₹100.00 /1KG
Minocycline CAS:10118-90-8
Varanous Labs Pvt Ltd PROTECH TELELINKS Maithri Drugs Pvt Ltd A.J Chemicals CLEARSYNTH LABS LTD. Pharmaffiliates Analytics and Synthetics P. Ltd Festiva Pharma
Capot Chemical Co.,Ltd.
Henan Tianfu Chemical Co.,Ltd.