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ChemicalBook > Product Catalogue >Analytical Chemistry >Standard >Standard Substance >Mirtazapine

Mirtazapine

Mirtazapine Structure
  • ₹0
  • Product name: Mirtazapine
  • CAS: 61337-67-5
  • MF: C17H19N3
  • MW: 265.35
  • EINECS:641-354-1
  • MDL Number:MFCD00865427
  • Synonyms:1,2,3,4,10,14B-HEXAHYDRO-2-METHYLPYRAZINO[2,1-A]PYRIDO[2,3-C][2]BENZAZEPINE;1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-α]pyrido[2,3-c][2]benzazepine;Mirtazepine, 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine;ORG-3770;MIRTAZANINE;MIRTAZEPINE;REMERON;1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c]benzazepine
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :114-116°C
Flash point :9℃
storage temp. :2-8°C
solubility :DMSO: ~8 mg/mL, soluble
form :solid
pka :pKa 7.1(47% MeOH in H2O,t =25,I=0.15(KCl)) (Uncertain)
color :white
CAS DataBase Reference :61337-67-5(CAS DataBase Reference)
NIST Chemistry Reference :Mirtazapine(61337-67-5)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P307+P311, P321,P405, P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P311 Call a POISON CENTER or doctor/physician.

Description

Mirtazapine is an antidepressant launched in the Netherlands. Mirtazapine is a potent antagonist of presynaptic α2 receptors as well as a moderately potent 5-HT antagonist. Studies suggested that blockade of α2-adrenoceptors, but not inhibition of noradrenaline uptake, is involved in the mechanism of the antidepressant action of mirtazapine. Mirtazapine has demonstrated efficacy in various studies in depressed patients, being equal or more potent than mianserin, amitriptyline, etc. and exhibiting less anticholinergic and gastrointestinal side effects and low cardiovascular toxicity. In addition to its antidepressant effects, studies in animals indicated that mirtazapine has anxiolytic andor hypnotic activity.

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Suppliers and manufacturers

Jigs Chemical ltd Aurobindo Pharma Limited Sun Pharmaceutical Industries Ltd HRV Global Life Sciences Adeep Life Sciences Pvt Ltd Megafine Pharma Basil Drugs AND Pharmaceuticals Pvt Ltd Almon Industries Ralington Pharma Alfa Omega Pharma