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ChemicalBook > Product Catalogue >API >Circulatory system drugs >Angina Pectoris Drugs >Tetramethylpyrazine

Tetramethylpyrazine

Tetramethylpyrazine Structure
  • ₹3200 - ₹315743.6
  • Product name: Tetramethylpyrazine
  • CAS: 1124-11-4
  • MF: C8H12N2
  • MW: 136.19
  • EINECS:214-391-2
  • MDL Number:MFCD00006146
  • Synonyms:BS Factor;tetramethyl-pyrazin ;FEMA NUMBER 3237;TETRAPYRAZINE;TETRAMETHYLPYRAZINE;2,3,5,6-TETRAMETHYLPYRAZINES;2,3,5,6-TETRAMETHYL-1,4-PYRAZINE;2,3,5,6-TetraMethylpyrazine 98%
11 prices
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 100MG
  • 25G
  • 100G
  • 250G
  • 1KG
  • 5KG
  • 1SAMPLE-K
  • ManufacturerTCI Chemicals (India)
  • Product numberT0972
  • Product description2,3,5,6-Tetramethylpyrazine min. 98.0 %
  • Packaging25G
  • Price₹3200
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number183938
  • Product description2,3,5,6-Tetramethylpyrazine 98%
  • Packaging25G
  • Price₹3485.65
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberW323705
  • Product description2,3,5,6-Tetramethylpyrazine ≥98%, FG
  • Packaging1SAMPLE-K
  • Price₹5141.88
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberW323713
  • Product description2,3,5,6-Tetramethylpyrazine natural, ≥98%, FG
  • Packaging1SAMPLE-K
  • Price₹5347.55
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number183938
  • Product description2,3,5,6-Tetramethylpyrazine 98%
  • Packaging100G
  • Price₹13163.2
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number95162
  • Product description2,3,5,6-Tetramethylpyrazine analytical standard
  • Packaging100MG
  • Price₹13542.08
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberW323705
  • Product description2,3,5,6-Tetramethylpyrazine ≥98%, FG
  • Packaging250G
  • Price₹15652.95
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberW323713
  • Product description2,3,5,6-Tetramethylpyrazine natural, ≥98%, FG
  • Packaging100G
  • Price₹41535.53
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberW323705
  • Product description2,3,5,6-Tetramethylpyrazine ≥98%, FG
  • Packaging1KG
  • Price₹43678.88
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberW323705
  • Product description2,3,5,6-Tetramethylpyrazine ≥98%, FG
  • Packaging5KG
  • Price₹171684.5
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberW323713
  • Product description2,3,5,6-Tetramethylpyrazine natural, ≥98%, FG
  • Packaging1KG
  • Price₹315743.6
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) T0972 2,3,5,6-Tetramethylpyrazine min. 98.0 % 25G ₹3200 2022-05-26 Buy
Sigma-Aldrich(India) 183938 2,3,5,6-Tetramethylpyrazine 98% 25G ₹3485.65 2022-06-14 Buy
Sigma-Aldrich(India) W323705 2,3,5,6-Tetramethylpyrazine ≥98%, FG 1SAMPLE-K ₹5141.88 2022-06-14 Buy
Sigma-Aldrich(India) W323713 2,3,5,6-Tetramethylpyrazine natural, ≥98%, FG 1SAMPLE-K ₹5347.55 2022-06-14 Buy
Sigma-Aldrich(India) 183938 2,3,5,6-Tetramethylpyrazine 98% 100G ₹13163.2 2022-06-14 Buy
Sigma-Aldrich(India) 95162 2,3,5,6-Tetramethylpyrazine analytical standard 100MG ₹13542.08 2022-06-14 Buy
Sigma-Aldrich(India) W323705 2,3,5,6-Tetramethylpyrazine ≥98%, FG 250G ₹15652.95 2022-06-14 Buy
Sigma-Aldrich(India) W323713 2,3,5,6-Tetramethylpyrazine natural, ≥98%, FG 100G ₹41535.53 2022-06-14 Buy
Sigma-Aldrich(India) W323705 2,3,5,6-Tetramethylpyrazine ≥98%, FG 1KG ₹43678.88 2022-06-14 Buy
Sigma-Aldrich(India) W323705 2,3,5,6-Tetramethylpyrazine ≥98%, FG 5KG ₹171684.5 2022-06-14 Buy
Sigma-Aldrich(India) W323713 2,3,5,6-Tetramethylpyrazine natural, ≥98%, FG 1KG ₹315743.6 2022-06-14 Buy

Properties

Melting point :77-80 °C(lit.)
Boiling point :190 °C(lit.)
Density :1.08
FEMA :3237 | 2,3,5,6-TETRAMETHYLPYRAZINE
refractive index :1.5880 (estimate)
Flash point :128-130°C/200mm
storage temp. :Sealed in dry,Room Temperature
solubility :4g/l
pka :3.20±0.10(Predicted)
form :Solid
color :White to Off-White
Odor :at 10.00 % in dipropylene glycol. nutty musty chocolate coffee cocoa brown lard burnt
Odor Type :nutty
Water Solubility :Soluble in water (4 g/L at 20°C).
JECFA Number :780
BRN :113100
Stability :Stable. Incompatible with strong acids, strong oxidizing agents.
InChIKey :FINHMKGKINIASC-UHFFFAOYSA-N
LogP :1.56
CAS DataBase Reference :1124-11-4(CAS DataBase Reference)
NIST Chemistry Reference :Pyrazine, tetramethyl-(1124-11-4)
EPA Substance Registry System :Tetramethylpyrazine (1124-11-4)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Tetramethylpyrazine (TMP) is a kind of alkaloids identified in Ligusticum wallichii FRANCH. It has various kinds of medical applications. It has long been used in China for the treatment of cardiovascular problems. It also has antiinflammatory and analgesic effect. It can be used for the treatment of diabetic peripheral neuropathy. Through effectively penetrating across the blood-brain barrier, it can exert its neuroprotection function which is useful for the treatment of ischemic brain injury. Moreover, it can eliminate superoxide anion and decreases nitric oxide production in human polymorphonuclear leukocytes.

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