Mitomycin C
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- ₹7000 - ₹219660.9
- Product name: Mitomycin C
- CAS: 50-07-7
- MF: C15H18N4O5
- MW: 334.33
- EINECS:200-008-6
- MDL Number:MFCD00078109
- Synonyms:Mitomycin C(Ametycine);Azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione, 6-amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl-;Mytomycin C;[1aR-(1aα,8β,8aα,8bα)]-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2',3':3,4]pyrrolo[1,2-α]indole-4,7-dione;6-Amino-1,1a,2,8,8a,8b-hexahydro-8-(hydroxymethyl)-8a-methox-5-methylazirino[2',3':3,4]pyrrolo[1,2-;MitonyycinC;[1aS-(1aα,8β,8aα,8bα)]-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione;8balpha)]-8aalph
12 prices
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Brand
- Sigma-Aldrich(India)
- TCI Chemicals (India)
- ottokemi
Package
- 2MG
- 5MG
- 10MG
- 5X2MG
- 10X2MG
- 25MG
- 50MG
- 50X2MG
- ManufacturerSigma-Aldrich(India)
- Product numberM0440
- Product descriptionMitomycin C from Streptomyces caespitosus ≥970 μg/mg (USP XXIV)
- Packaging5MG
- Price₹8237.83
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberM7949
- Product descriptionMitomycin C from Streptomyces caespitosus ≥98% (HPLC), potency: ≥970?μg per mg (USP XXIV), γ-irradiated, suitable for cell culture
- Packaging2MG
- Price₹10543.55
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberM0503
- Product descriptionMitomycin C from Streptomyces caespitosus powder, contains NaCl as solubilizer
- Packaging2MG
- Price₹14386.43
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberM4287
- Product descriptionMitomycin C from Streptomyces caespitosus powder, BioReagent, suitable for cell culture
- Packaging2MG
- Price₹15046.75
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberM0503
- Product descriptionMitomycin C from Streptomyces caespitosus powder, contains NaCl as solubilizer
- Packaging5X2MG
- Price₹38731.85
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberM0440
- Product descriptionMitomycin C from Streptomyces caespitosus ≥970 μg/mg (USP XXIV)
- Packaging25MG
- Price₹39955.08
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberM4287
- Product descriptionMitomycin C from Streptomyces caespitosus powder, BioReagent, suitable for cell culture
- Packaging5X2MG
- Price₹67244.9
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberM0503
- Product descriptionMitomycin C from Streptomyces caespitosus powder, contains NaCl as solubilizer
- Packaging10X2MG
- Price₹72181.1
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberM0503
- Product descriptionMitomycin C from Streptomyces caespitosus powder, contains NaCl as solubilizer
- Packaging50X2MG
- Price₹219660.9
- Updated2022-06-14
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberM2320
- Product descriptionAmetycin
- Packaging50MG
- Price₹25400
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberM2320
- Product descriptionAmetycin
- Packaging10MG
- Price₹7000
- Updated2022-05-26
- Buy
- Manufacturerottokemi
- Product number M 2292
- Product descriptionMitomycin C
- Packaging2mg
- Price₹14409
- Updated2022-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | M0440 | Mitomycin C from Streptomyces caespitosus ≥970 μg/mg (USP XXIV) | 5MG | ₹8237.83 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | M7949 | Mitomycin C from Streptomyces caespitosus ≥98% (HPLC), potency: ≥970?μg per mg (USP XXIV), γ-irradiated, suitable for cell culture | 2MG | ₹10543.55 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | M0503 | Mitomycin C from Streptomyces caespitosus powder, contains NaCl as solubilizer | 2MG | ₹14386.43 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | M4287 | Mitomycin C from Streptomyces caespitosus powder, BioReagent, suitable for cell culture | 2MG | ₹15046.75 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | M0503 | Mitomycin C from Streptomyces caespitosus powder, contains NaCl as solubilizer | 5X2MG | ₹38731.85 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | M0440 | Mitomycin C from Streptomyces caespitosus ≥970 μg/mg (USP XXIV) | 25MG | ₹39955.08 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | M4287 | Mitomycin C from Streptomyces caespitosus powder, BioReagent, suitable for cell culture | 5X2MG | ₹67244.9 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | M0503 | Mitomycin C from Streptomyces caespitosus powder, contains NaCl as solubilizer | 10X2MG | ₹72181.1 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | M0503 | Mitomycin C from Streptomyces caespitosus powder, contains NaCl as solubilizer | 50X2MG | ₹219660.9 | 2022-06-14 | Buy |
| TCI Chemicals (India) | M2320 | Ametycin | 50MG | ₹25400 | 2022-05-26 | Buy |
| TCI Chemicals (India) | M2320 | Ametycin | 10MG | ₹7000 | 2022-05-26 | Buy |
| ottokemi | M 2292 | Mitomycin C | 2mg | ₹14409 | 2022-05-26 | Buy |
Properties
Melting point :360 °C
Boiling point :471.14°C (rough estimate)
Density :1.2238 (rough estimate)
refractive index :1.6800 (estimate)
storage temp. :2-8°C
solubility :H2O: 4 mL/vial Stock solutions should be filter sterilized and stored at 2-8 °C in the dark., clear to slightly hazy, blue to purple
form :powder
pka :pKa 2.8(H2O,t =25,I=0.1) (Uncertain)
color :blue-gray
PH :pH (0.5 g/l, 25℃ : )5.0～7.0
Water Solubility :soluble
Merck :14,6215
BRN :7231816
Stability :Stable. Incompatible with strong acids, strong bases, strong oxidizing agents.
CAS DataBase Reference :50-07-7(CAS DataBase Reference)
IARC :2B (Vol. 10, Sup 7) 1987
EPA Substance Registry System :Mitomycin C (50-07-7)
Boiling point :471.14°C (rough estimate)
Density :1.2238 (rough estimate)
refractive index :1.6800 (estimate)
storage temp. :2-8°C
solubility :H2O: 4 mL/vial Stock solutions should be filter sterilized and stored at 2-8 °C in the dark., clear to slightly hazy, blue to purple
form :powder
pka :pKa 2.8(H2O,t =25,I=0.1) (Uncertain)
color :blue-gray
PH :pH (0.5 g/l, 25℃ : )5.0～7.0
Water Solubility :soluble
Merck :14,6215
BRN :7231816
Stability :Stable. Incompatible with strong acids, strong bases, strong oxidizing agents.
CAS DataBase Reference :50-07-7(CAS DataBase Reference)
IARC :2B (Vol. 10, Sup 7) 1987
EPA Substance Registry System :Mitomycin C (50-07-7)
Safety Information
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| Signal word: | Danger | |||||||||||||||||||||
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Description
Mitomycin C (MMC), an antineoplastic antibiotic derived from Streptomyces caespitosus or Streptomyces lavendulae, is a cell cycle-specific alkylating agent, inhibits DNA synthesis through covalent mitomycin C-DNA adduct with EC50 values of 0.14μM in PC3 cells. Therefore, it was served as a chemotherapeutic agent that has demonstrated its antitumor activity and has been used widely in treatment of various cancers.Although it is active against a wide variety of tumors, newer agents have largely replaced MMC except in anal cancer; outside of the United States, MMC is infrequently used for treatment of advanced non-small cell lung cancer (NSCLC), and breast cancer.
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