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ChemicalBook > Product Catalogue >API >Antibiotics >Lincosamides Drugs >Clindamycin

Clindamycin

Clindamycin Structure
  • ₹0
  • Product name: Clindamycin
  • CAS: 18323-44-9
  • MF: C18H33ClN2O5S
  • MW: 424.98
  • EINECS:242-209-1
  • MDL Number:MFCD00072005
  • Synonyms:Clindamycin (base and/or unspecified salts);(2S,4R)-N-[(1S,2S)-2-Chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide;CLDM;Methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S)-1-methyl-4β-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-L-threo-α-D-galacto-octopyranoside;Methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-L-threo-α-D-galacto-octopyranoside;U-21251;Clindamycin Base;7-Chloro-7-deoxylincoMycin, 7-ChlorolincoMycin
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

alpha :D +214° (chloroform)
Boiling point :134°C (rough estimate)
Density :1.1184 (rough estimate)
refractive index :1.6100 (estimate)
storage temp. :Store at -20°C
solubility :DMSO:52.5(Max Conc. mg/mL);123.54(Max Conc. mM)
DMF:30.0(Max Conc. mg/mL);70.59(Max Conc. mM)
Ethanol:52.5(Max Conc. mg/mL);123.54(Max Conc. mM)
PBS (pH 7.2):0.2(Max Conc. mg/mL);0.47(Max Conc. mM) form :A crystalline solid
pka :7.6(at 25℃)
color :White to light yellow
BCS Class :1
Stability :Hygroscopic
CAS DataBase Reference :18323-44-9(CAS DataBase Reference)
EPA Substance Registry System :L-threo-?-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio- (18323-44-9)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H362 May cause harm to breast-fed children Reproductive toxicity, effects on or via lactation Additional category P201, P260, P263, P264, P270,P308+P313
Precautionary statements:
P201 Obtain special instructions before use.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P263 Avoid contact during pregnancy/while nursing.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Clindamycin is an antibiotic in the lincosamide class which binds the bacterial 50S ribosomal subunit and interferes with protein synthesis. Evidence suggests that clindamycin is particularly effective against anaerobes and is commonly used against Gram positive bacteria. It is used for serious infections and in the prevention of emerging infections in burns. Clindamycin is also effective against P. falciparum and is used as an antimalarial, either alone or in combination therapy.

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Suppliers and manufacturers

CHEMXTREE STANDARDS PROTECH TELELINKS CLEARSYNTH LABS LTD. Triveni chemicals Pharmaffiliates Analytics and Synthetics P. Ltd Jigs Chemical Limited Mahir Technologies Inc. Chemland Ind Karthik Enterprises Taj Mahal Vision Chemicals Private Limited