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ChemicalBook > Product Catalogue >API >Hormones and the Endocrine System >Prostaglandin drugs >Misoprostol

Misoprostol

Misoprostol Structure
  • ₹20480.9
  • Product name: Misoprostol
  • CAS: 59122-46-2
  • MF: C22H38O5
  • MW: 382.54
  • EINECS:664-288-5
  • MDL Number:MFCD07772001
  • Synonyms:DL-MISOPROSTOL;Misoprostol API;Misogon;Misoprostil;Misoprostol, 1% in cellulose;SC 2933;Prost-13-en-1-oic acid, 11,16-dihydroxy-16-methyl-9-oxo-, methyl ester, (11a,13E)- (9CI);(11α，13E)-1l，16-Dihydroxy-16-methyl-9-oxoprost-13-en-1-oic acid methyl ester
Price1 Properties Safety Information Description
1 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 10MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberM6807
  • Product descriptionMisoprostol ≥99% (HPLC)
  • Packaging10MG
  • Price₹20480.9
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) M6807 Misoprostol ≥99% (HPLC) 10MG ₹20480.9 2022-06-14 Buy

Properties

Melting point :261-263°C
Boiling point :429.67°C (rough estimate)
Density :1.0323 (rough estimate)
refractive index :1.6120 (estimate)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :Practically insoluble in water, soluble in ethanol (96 per cent), sparingly soluble in acetonitrile.
pka :13.92±0.60(Predicted)
CAS DataBase Reference :59122-46-2(CAS DataBase Reference)
EPA Substance Registry System :Misoprostol (59122-46-2)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P201 Obtain special instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Misoprostol is a PGE1 analog with agonist activity mediated by EP2, EP3, and EP4 receptors. It has been shown to inhibit the formation of gastric lesions in rats (ED50 = 0.31 μg/kg), inhibit superoxide generation in human neutrophils (EC50 = 0.35 μM), and relax fetal rabbit ductus arteriosus (EC50 = 0.36 nM) in a concentration dependent manner. Misoprostol is commonly used in clinical medicine for the prevention of peptic ulcer disease. It has also been used in conjunction with RU-486 for the oral induction of first trimester abortion. Misoprostol is readily absorbed and rapidly hydrolyzed in humans to the active free acid.

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BTC pharm India Aptus Therapeutics Sonia Organics Honour Lab Limited Avra Laboratories Pvt Ltd ANVI Pharma Chempifine Chemicals Fleming Laboratories Ltd Besil Chem LLP Alfa Omega Pharma