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ChemicalBook > Product Catalogue >API >Hormones and the Endocrine System >Pancreatic hormone and blood sugar regulation >Mitiglinide calcium

Mitiglinide calcium

Mitiglinide calcium Structure
  • ₹4800 - ₹31987.88
  • Product name: Mitiglinide calcium
  • CAS: 145525-41-3
  • MF: (C19H24NO3)2.Ca
  • MW: 668.88
  • EINECS:692-046-9
  • MDL Number:MFCD08458378
  • Synonyms:calcium 2-benzyl-3-(cis-hexahydro-2-isoindolinylcarbonyl)propionate;(as,3ar,7as)-octahydro-gamma-oxo-alpha-(phenylmethyl)-2h-isoindole-2-butanoic acid calcium salt dihydrate;MITIGLINIDE CALCIUM HYDRATE;MITIGLINIDECALCIUM(FORR&DONLY);Monocalcium bis[(2S)-2-benzyl-3-(cis-hexahydro isoindolin -2-carbonyl)propionate]dihydrate;MITIGLINIDE KAD-1229;Mitiglinide calcium;Mitiglinide calcium anhydrous
4 prices
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • 100MG
  • 500MG
  • ManufacturerTCI Chemicals (India)
  • Product numberM3177
  • Product descriptionMitiglinide Calcium
  • Packaging100MG
  • Price₹4800
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberM3177
  • Product descriptionMitiglinide Calcium
  • Packaging500MG
  • Price₹8800
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0234
  • Product descriptionMitiglinide calcium ≥98% (HPLC)
  • Packaging10MG
  • Price₹8086.28
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0234
  • Product descriptionMitiglinide calcium ≥98% (HPLC)
  • Packaging50MG
  • Price₹31987.88
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) M3177 Mitiglinide Calcium 100MG ₹4800 2022-05-26 Buy
TCI Chemicals (India) M3177 Mitiglinide Calcium 500MG ₹8800 2022-05-26 Buy
Sigma-Aldrich(India) SML0234 Mitiglinide calcium ≥98% (HPLC) 10MG ₹8086.28 2022-06-14 Buy
Sigma-Aldrich(India) SML0234 Mitiglinide calcium ≥98% (HPLC) 50MG ₹31987.88 2022-06-14 Buy

Properties

Melting point :146-148°C
Density :1.175
storage temp. :Inert atmosphere,Room Temperature
solubility :DMSO: ≥10mg/mL at warmed to 60°C
form :powder
color :white to beige
optical activity :[α]/D +5 to +9° (c=1, MeOH)
CAS DataBase Reference :145525-41-3(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P273 Avoid release to the environment.
P501 Dispose of contents/container to..…

Description

Mitiglinide is the calcium salt form of Mitiglinide, which is a drug for the treatment of type II diabetes. It belongs to the meglitinide class blood glucose-lowering drug. Its mechanism of action is through stimulating the insulin secretion through closing the ATP-sensitive potassium channels in the pancreatic beta-cells. This process leads to depolarization, further stimulating the influx of calcium through the voltage-gated calcium channels. The high intracellular calcium level results in the exocytosis of insulin granules, alleviating the symptoms of type II diabetes.

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