ChemicalBook > Product Catalog >API >Hormones and the Endocrine System >Pancreatic hormone and blood sugar regulation >Mitiglinide calcium
Mitiglinide calcium
- CAS No.
- 145525-41-3
- Chemical Name:
- Mitiglinide calcium
- Synonyms
- S21403;S 21403;S-21403;Mitiglinide calcium;Mitiglinide Calcium RS;MITIGLINIDE KAD-1229;Mitiglinide Calcium Salt;MITIGLINIDE CALCIUM HYDRATE;Mitiglinide hemicalcium salt;Mitiglinide calcium anhydrous
- CBNumber:
- CB8854809
- Molecular Formula:
- (C19H24NO3)2.Ca
- Molecular Weight:
- 668.88
- MOL File:
- 145525-41-3.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/8 17:06:36
| Melting point | 146-148°C |
|---|---|
| Density | 1.175 |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | DMSO: ≥10mg/mL at warmed to 60°C |
| form | powder |
| color | white to beige |
| optical activity | [α]/D +5 to +9° (c=1, MeOH) |
| CAS DataBase Reference | 145525-41-3(CAS DataBase Reference) |
Mitiglinide calcium price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | SML0234 | Mitiglinide calcium ≥98% (HPLC) | 145525-41-3 | 10MG | ₹8086.28 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SML0234 | Mitiglinide calcium ≥98% (HPLC) | 145525-41-3 | 50MG | ₹31987.88 | 2022-06-14 | Buy |
| TCI Chemicals (India) | M3177 | Mitiglinide Calcium | 145525-41-3 | 100MG | ₹4800 | 2022-05-26 | Buy |
| TCI Chemicals (India) | M3177 | Mitiglinide Calcium | 145525-41-3 | 500MG | ₹8800 | 2022-05-26 | Buy |
Mitiglinide calcium Chemical Properties,Uses,Production
Uses
Mitiglinide Calcium is a blood glucose-lowering drugs, stimulating insulin secretion by closing the ATP-sensitive K+ channels in pancreatic beta-cells
Mode of action
Mitiglinide is another non-sulfonylurea insulin secretagogue. Insulin secretion is physiologically stimulated by the binding of ATP to a cytosolic nucleotide binding site of the membrane bound ATP-sensitive K+ channel which leads to closure of the K+ channel. The inhibition of K+ permeability depolarizes the plasma membrane, subsequently the voltage-dependent Ca2+ channel opens to promote the Ca2+ influx which finally results in insulin secretion. The insulin secretagogues stimulate insulin secretion by closure of this ATP-sensitive K+ channel of pancreatic -cells. KATP-channel consists of two subunits, a functional ion channel pore and a regulatory protein. The binding of the secretagogues is suggested to occur to the separate regulator protein containing the binding sites for sulfonylureas (sulfonylurea receptor 1, SUR1) but also other compounds.
Mitiglinide calcium Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 245)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21677 | 55 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29901 | 58 | Inquiry |
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | China | 6387 | 58 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
| SIMAGCHEM CORP | +86-13806087780 | China | 17367 | 58 | Inquiry |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | China | 9077 | 58 | Inquiry |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 26415 | 58 | Inquiry |
145525-41-3(Mitiglinide calcium)Related Search:
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calcium 2-benzyl-3-(cis-hexahydro-2-isoindolinylcarbonyl)propionate
(as,3ar,7as)-octahydro-gamma-oxo-alpha-(phenylmethyl)-2h-isoindole-2-butanoic acid calcium salt dihydrate
MITIGLINIDE CALCIUM HYDRATE
MITIGLINIDECALCIUM(FORR&DONLY)
Monocalcium bis[(2S)-2-benzyl-3-(cis-hexahydro isoindolin -2-carbonyl)propionate]dihydrate
MITIGLINIDE KAD-1229
Mitiglinide calcium
Mitiglinide calcium anhydrous
(αS,3aR,7aS)-Octahydro-γ-oxo-α-(phenylmethyl)-2H-isoindole-2-butanoic acid, calcium salt (2:1)
[2(S)-cis]-octahydro-γ-oxo-α-(phenylmethyl)-2H-Isoindole-2-buta
octahydro-γ-oxo-α-(phenylmethyl)-2H-Isoindole-2-butanoic acid, calcium salt, (αS,3aR,7aS)- (9CI)
2H-Isoindole-2-butanoicacid, octahydro-g-oxo-a-(phenylMethyl)-, calciuM salt (2:1), (aS,3aR,7aS)-
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S 21403
S21403
S-21403
CalciuM (S)-2-benzyl-4-((3aR,7aS)-hexahydro-1H-isoindol-2(3H)-yl)-4-oxobutanoate
(aS,3aR,7aS)-Octahydro-g-oxo-a-(phenylmethyl)-2H-isoindole-2-butanoic acid calcium salt
[2(S)-cis]-Octahydro-g-oxo-a-(phenylmethyl)-2H-isoindole-2-butanoic acid calclium salt
Mitiglinide hemicalcium salt
Mitiglinide calcium chloride dihydrate
(alphaS,3aR,7aS)-Octahydro-γ-oxo-α-(phenylmethyl)-2H-isoindole-2-butanoic Acid Calcium Salt
calcium 4-(1,3,3a,4,5,6,7,7a-octahydroisoindol-2-yl)-4-oxo-2-(phenylmethyl)butanoate
(2S)-Mitiglinide-d5 Calcium Salt
Mitiglinide Calcium RS
Mitiglinide Calcium Salt
(alphaS,3aR,7aS)-Octahydro-gamma-oxo-alpha-(phenylmethyl)-2H-isoindole-2-butanoic Acid Calcium Salt
Mitiglinide calcium USP/EP/BP
Mitiglinide Calcium (KAD-1229)
TIANFU CHEM-- Mitiglinide calcium
Calcium (S)-2-benzyl-4-((3aR,7aS)-octahydro-2H-isoindol-2-yl)-4-oxobutanoate
2H-Isoindole-2-butanoic acid, octahydro-γ-oxo-α-(phenylmethyl)-, calcium salt (2:1), (αS,3aR,7aS)-
(alphaS,3aR,7aS)-Octahydro-γ-oxo-α-(phenylmethyl)-2H-isoindole-2-butanoic Acid Calcium Salt
145525-41-3
900-61-9
122322-18-7
C19H24NO32Ca
C38H52CaN2O8
2C19H24NO3Ca
C38H48CaN2O6
C38H48CaN2O62H2O
C19H25NO32Ca2H2O
C19H24NO312Ca
C19H25CaNO3
Inhibitors
API
White crystal posder
Pharmaceutical material and intermeidates