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ChemicalBook > Product Catalogue >API >Circulatory system drugs >Anti Shock vasoactive drugs >Olanzapine

Olanzapine

Olanzapine Structure
  • ₹7200 - ₹38417.93
  • Product name: Olanzapine
  • CAS: 132539-06-1
  • MF: C17H20N4S
  • MW: 312.43
  • EINECS:603-618-4
  • MDL Number:MFCD00866702
  • Synonyms:4-Amino-2-methyl-10H-Thineo(2,3b)(1,5)benzodiazepine HCL;2-Methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-β][1,5]benzodiazepine, LY-170053, Zyprexa;2-Methyl-4-(4-methyl-1-pipemzinyl)-10H-thieno[2,3-b][1,5]benzodiazepine;2-Methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine;Olanzapine(Zyprexa);Oliza;2-Methyl-4-(4-Methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiaze;Olanzapine (LY170053)
6 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • 1G
  • 1ML
  • 5G
  • ManufacturerTCI Chemicals (India)
  • Product numberO0393
  • Product descriptionOlanzapine min. 98.0 %
  • Packaging1G
  • Price₹7200
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberO0393
  • Product descriptionOlanzapine min. 98.0 %
  • Packaging5G
  • Price₹16300
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberO-024
  • Product descriptionOlanzapine solution 1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant?
  • Packaging1ML
  • Price₹8751.4
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberO1141
  • Product descriptionOlanzapine ≥98% (HPLC)
  • Packaging10MG
  • Price₹10110.55
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1825
  • Product descriptionOlanzapine Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging1G
  • Price₹18954.58
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberO1141
  • Product descriptionOlanzapine ≥98% (HPLC)
  • Packaging50MG
  • Price₹38417.93
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) O0393 Olanzapine min. 98.0 % 1G ₹7200 2022-05-26 Buy
TCI Chemicals (India) O0393 Olanzapine min. 98.0 % 5G ₹16300 2022-05-26 Buy
Sigma-Aldrich(India) O-024 Olanzapine solution 1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant? 1ML ₹8751.4 2022-06-14 Buy
Sigma-Aldrich(India) O1141 Olanzapine ≥98% (HPLC) 10MG ₹10110.55 2022-06-14 Buy
Sigma-Aldrich(India) PHR1825 Olanzapine Pharmaceutical Secondary Standard; Certified Reference Material 1G ₹18954.58 2022-06-14 Buy
Sigma-Aldrich(India) O1141 Olanzapine ≥98% (HPLC) 50MG ₹38417.93 2022-06-14 Buy

Properties

Melting point :195°C
Boiling point :476.0±55.0 °C(Predicted)
Density :1.32±0.1 g/cm3(Predicted)
Flash point :2℃
storage temp. :2-8°C
solubility :DMSO: >15mg/mL
form :powder
pka :7.78±0.20(Predicted)
color :yellow
Merck :14,6822
BRN :7655141
BCS Class :2
CAS DataBase Reference :132539-06-1(CAS DataBase Reference)
NIST Chemistry Reference :Olanzapine(132539-06-1)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

Olanzapine is an antipsychotic, thienobenzodiazepine compound that has been approved for use in the treatment of schizophrenia and bipolar disorder (formulated for human use under the name Zyprexa?). Olanzapine binds as an antagonist/inverse agonist to dopamine D1 (Ki = 31 nM), dopamine D2 (Ki = 11 nM), dopamine D4 (Ki = 27 nM), serotonin 5-HT2A (Ki = 4 nM), serotonin 5-HT2C (Ki = 11 nM), serotonin 5-HT3 (Ki = 57 nM), muscarinic M1 (Ki = 2 nM), α1-adrenergic (Ki = 19 nM), and histamine H1 (Ki = 7 nM) receptors. Olanzapine has a high affinity for dopamine D1 and D2 receptors (IC50s = 25 and 10 nM, respectively) in human striatal tissue and for 5-HT2A, 5-HT2C, muscarinic M1, and α1-adrenergic receptors (IC50s = 7, 71, 2, and 70 nM, respectively) in human frontal cortex. This product is intended for research purposes only.

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