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ChemicalBook > Product Catalogue >API >Digestive system drugs >Appetite suppressants and other diet pills >Orlistat

Orlistat

Orlistat Structure
  • ₹7900 - ₹54666.25
  • Product name: Orlistat
  • CAS: 96829-58-2
  • MF: C29H53NO5
  • MW: 495.73
  • EINECS:639-755-1
  • MDL Number:MFCD05662360
  • Synonyms:RO-18-0647;(-)-TETRAHYDROLIPSTATIN;ORLISTAT;Orlistat(synthesis);Orlistat(FerMentation);S,S,S,S-Orlistat;(2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl (2S)-2-forMaMido-4-Methylpentanoate;oristat
7 prices
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)
  • ottokemi

Package

  • 25MG
  • 100MG
  • 1G
  • ManufacturerTCI Chemicals (India)
  • Product numberO0381
  • Product descriptionOrlistat
  • Packaging100MG
  • Price₹7900
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberO0381
  • Product descriptionOrlistat
  • Packaging1G
  • Price₹34000
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberO4139
  • Product descriptionOrlistat ≥98%, solid
  • Packaging25MG
  • Price₹13671.98
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1445
  • Product descriptionOrlistat Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging1G
  • Price₹14992.63
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberO4139
  • Product descriptionOrlistat ≥98%, solid
  • Packaging100MG
  • Price₹54666.25
  • Updated2022-06-14
  • Buy
  • Manufacturerottokemi
  • Product number O 0392
  • Product descriptionOrlistat, ≥98%
  • Packaging25mg
  • Price₹10404
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number O 0392
  • Product descriptionOrlistat, ≥98%
  • Packaging100mg
  • Price₹41706
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) O0381 Orlistat 100MG ₹7900 2022-05-26 Buy
TCI Chemicals (India) O0381 Orlistat 1G ₹34000 2022-05-26 Buy
Sigma-Aldrich(India) O4139 Orlistat ≥98%, solid 25MG ₹13671.98 2022-06-14 Buy
Sigma-Aldrich(India) PHR1445 Orlistat Pharmaceutical Secondary Standard; Certified Reference Material 1G ₹14992.63 2022-06-14 Buy
Sigma-Aldrich(India) O4139 Orlistat ≥98%, solid 100MG ₹54666.25 2022-06-14 Buy
ottokemi O 0392 Orlistat, ≥98% 25mg ₹10404 2022-05-26 Buy
ottokemi O 0392 Orlistat, ≥98% 100mg ₹41706 2022-05-26 Buy

Properties

Melting point :<50 °C
Boiling point :615.9±30.0 °C(Predicted)
alpha :D20 -32.0° (c = 1 in chloroform)
Density :0.976±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: 19 mg/mL
form :solid
pka :14.59±0.23(Predicted)
color :white
Merck :14,6869
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 week.
InChIKey :AHLBNYSZXLDEJQ-FWEHEUNISA-N
SMILES :C(O[C@H](C[C@H]1[C@H](CCCCCC)C(=O)O1)CCCCCCCCCCC)(=O)[C@H](CC(C)C)NC=O
CAS DataBase Reference :96829-58-2(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H412 Harmful to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 3 P273, P501
Precautionary statements:
P273 Avoid release to the environment.

Description

Orlistat, used in obesity research, is a pancreatic lipase inhibitor that acts locally in the gastrointestinal tract to inhibit lipase. More detailed experiments show that gradually THL affects the retinoblastoma protein pathway and leads to cell-cycle arrest at G1/S boundary. Lipase Inhibitor, THL is an inhibitor of pancreatic and gastric lipase, as well as carboxyl ester lipase (CEL) and diacylglycerol lipase-α (DAGLα). Lipase Inhibitor, THL also activates caspase-3.

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