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ChemicalBook > Product Catalogue >Pharmaceutical intermediates >Heterocyclic compound >Pyrimidines >Phenylpyrimidine >PP3

PP3

PP3 Structure
  • ₹3400 - ₹9800
  • Product name: PP3
  • CAS: 5334-30-5
  • MF: C11H9N5
  • MW: 211.22
  • EINECS:
  • MDL Number:MFCD00022901
  • Synonyms:4-AMINO-7-PHENYLPYRAZOL[3,4-D]PYRIMIDINE;4-AMINO-1-PHENYLPYRAZOLE[3,4-D]PYRIMIDINE;4-AMINO-1-PHENYLPYRAZOLO[3,4-D]PYRIMIDINE;1-PHENYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE;PP3;1-Phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine;4-Amino-1-phenylpyrazolo3,4-düpyrimidine, tech. 85%;4-AMINO-1-PHENYLPYRAZOLO[3,4-D]PYRIMIDINE: TECH., 85%
2 prices
Selected condition:

Brand

  • TCI Chemicals (India)

Package

  • 200MG
  • 1G
  • ManufacturerTCI Chemicals (India)
  • Product numberA2737
  • Product description4-Amino-1-phenylpyrazolo[3,4-d]pyrimidine
  • Packaging200MG
  • Price₹3400
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberA2737
  • Product description4-Amino-1-phenylpyrazolo[3,4-d]pyrimidine
  • Packaging1G
  • Price₹9800
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) A2737 4-Amino-1-phenylpyrazolo[3,4-d]pyrimidine 200MG ₹3400 2022-05-26 Buy
TCI Chemicals (India) A2737 4-Amino-1-phenylpyrazolo[3,4-d]pyrimidine 1G ₹9800 2022-05-26 Buy

Properties

Melting point :214-217 °C
storage temp. :-20°C
solubility :DMF, DMSO, Hot methanol
form :Off-white solid
color :Whit to Off-White
λmax :240nm(H2O (pH 1))(lit.)
BRN :198460
CAS DataBase Reference :5334-30-5(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

The Src family of non-receptor tyrosine kinases regulate cell adhesion, growth, and differentiation through activation of multiple intracellular signaling pathways. Normally inactive, Src kinases are transiently activated during mitosis and constitutively activated by abnormal mutations. Several small molecule inhibitors of this signaling pathway have been developed as a therapeuptic strategy to abate abnormal Src kinase activity. PP3 is an inactive analog of the Src tyrosine kinase inhibitors PP1 and PP2 . At concentrations as high as 10 μM, it does not prevent proliferation mediated by a stem cell factor/mast cell growth factor in hematopoietic and cancer cell lines.

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