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ChemicalBook > Product Catalogue >Pharmaceutical intermediates >Bulk Drug Intermediates >PROSTAGLANDIN F1ALPHA

PROSTAGLANDIN F1ALPHA

PROSTAGLANDIN F1ALPHA Structure
  • ₹0
  • Product name: PROSTAGLANDIN F1ALPHA
  • CAS: 745-62-0
  • MF: C20H36O5
  • MW: 356.5
  • EINECS:234-237-8
  • MDL Number:MFCD00077862
  • Synonyms:prostaglandinf1 ;protaglandinf1 ;PROSTAGLANDIN F1A;syntheticwhitecrystallinesolid;(9α,11α,13e,15s)-9,11,15-trihydroxyprost-13-en-1-oic acid;(9a,11a,13E,15S)- 9,11,15-trihydroxy-Prost-13-en-1-oic acid;PGF1α, (9α,11α,13E,15S)-9,11,15-Trihydroxyprost-13-en-1-oic acid;(13E,15S)-9α,11α,15-Trihydroxyprost-13-en-1-oic acid
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :102.5°C
Boiling point :409.31°C (rough estimate)
alpha :+24°(D/24℃)(c=0.87,THF)
Density :1.0321 (rough estimate)
refractive index :1.6120 (estimate)
storage temp. :-20°C
solubility :DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS pH 7.2: 2 mg/ml
form :A crystalline solid
pka :4.78±0.10(Predicted)
BRN :2704846

Safety Information

Symbol(GHS):
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Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
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Description

Prostaglandin F1α (PGF1α) is the putative metabolite of dihomo-γ-linolenic acid (DGLA) via the cyclooxygenase (COX) pathway. Both PGF1α and PGF2α have been shown to act as priming pheromones for male Atlantic salmon with a threshold concentration of 10?11 M. PGF1α binds to the ovine corpus luteum FP receptor at only 8% of the relative potency of PGF2α. It is only half as active as PGF2α in inducing human respiratory smooth muscle contractions in vitro.

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