Pidotimod
- ₹8000 - ₹43613.93
- Product name: Pidotimod
- CAS: 121808-62-6
- MF: C9H12N2O4S
- MW: 244.27
- EINECS:2017-001-1
- MDL Number:MFCD00867583
- Synonyms:(4R)-3-[(2S)-5-Oxopyrrolidine-2-carbonyl]-1,3-thiazolidine-4-carboxylic acid;(4S)-3-(5-Oxo-L-prolyl)thiazolidine-4-carboxylic acid;3-Pyroglutamoylthiazolidine-4-carboxylic acid;(4R)-3-[(2S)-5-ketopyrrolidine-2-carbonyl]thiazolidine-4-carboxylic acid;(4R)-3-[(2S)-5-oxopyrrolidin-2-yl]carbonyl-1,3-thiazolidine-4-carboxylic acid;(R)-3-((S)-5-Oxopyrrolidine-2-carbonyl)thiazolidine-4-carboxylic acid;Axil;Onaka
4 prices
Selected condition:
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 50MG
- 250MG
- 5G
- 25G
- ManufacturerTCI Chemicals (India)
- Product numberP2147
- Product descriptionPidotimod
- Packaging5G
- Price₹8000
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberP2147
- Product descriptionPidotimod
- Packaging25G
- Price₹16300
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML1335
- Product descriptionPidotimod ≥98% (HPLC)
- Packaging50MG
- Price₹10825
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML1335
- Product descriptionPidotimod ≥98% (HPLC)
- Packaging250MG
- Price₹43613.93
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
TCI Chemicals (India) | P2147 | Pidotimod | 5G | ₹8000 | 2022-05-26 | Buy |
TCI Chemicals (India) | P2147 | Pidotimod | 25G | ₹16300 | 2022-05-26 | Buy |
Sigma-Aldrich(India) | SML1335 | Pidotimod ≥98% (HPLC) | 50MG | ₹10825 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | SML1335 | Pidotimod ≥98% (HPLC) | 250MG | ₹43613.93 | 2022-06-14 | Buy |
Properties
Melting point :194-198°C (dec.)
alpha :D25 -150° (c = 2 in 5N HCl)
Boiling point :663.0±55.0 °C(Predicted)
Density :1.53
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :DMSO (Slightly, Heated), Methanol (Slightly, Heated), 5N HCl (Slightly)
form :powder
pka :3.03(at 25℃)
color :white to beige
optical activity :[α]/D -135 to -155°, c = 1 in 6 M HCl
Merck :14,7419
InChI :InChI=1S/C9H12N2O4S/c12-7-2-1-5(10-7)8(13)11-4-16-3-6(11)9(14)15/h5-6H,1-4H2,(H,10,12)(H,14,15)/t5-,6-/m0/s1
InChIKey :UUTKICFRNVKFRG-WDSKDSINSA-N
SMILES :S1C[C@@H](C(O)=O)N(C([C@@H]2CCC(=O)N2)=O)C1
CAS DataBase Reference :121808-62-6(CAS DataBase Reference)
alpha :D25 -150° (c = 2 in 5N HCl)
Boiling point :663.0±55.0 °C(Predicted)
Density :1.53
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :DMSO (Slightly, Heated), Methanol (Slightly, Heated), 5N HCl (Slightly)
form :powder
pka :3.03(at 25℃)
color :white to beige
optical activity :[α]/D -135 to -155°, c = 1 in 6 M HCl
Merck :14,7419
InChI :InChI=1S/C9H12N2O4S/c12-7-2-1-5(10-7)8(13)11-4-16-3-6(11)9(14)15/h5-6H,1-4H2,(H,10,12)(H,14,15)/t5-,6-/m0/s1
InChIKey :UUTKICFRNVKFRG-WDSKDSINSA-N
SMILES :S1C[C@@H](C(O)=O)N(C([C@@H]2CCC(=O)N2)=O)C1
CAS DataBase Reference :121808-62-6(CAS DataBase Reference)
Safety Information
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Description
Pidotimod is a synthetic dipeptide with immunomodulatory properties on both innate and adaptive immune responses in in vitro studies. It has been shown to induce dendritic cell (DC) maturation, to upregulate the expression of HLA-DR and co-stimulatory molecules CD83 and CD86, to stimulate the release of pro-inflammatory molecules from DCs, which drives T cell proliferation and differentiation towards a Th1 phenotype, to enhance natural killer cell functions, to inhibit thymocyte apoptosis, and to promote phagocytosis. Through separate effects on ERK1/2 and NF-κB, pidotimod was shown to increase the expression of toll-like receptor 2 proteins. Pimotimod does not affect expression of ICAM-1 or the release of IL-8.Related product price
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