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RAC 8-HYDROXY EFAVIRENZ

RAC 8-HYDROXY EFAVIRENZ Structure
  • ₹0
  • Product name: RAC 8-HYDROXY EFAVIRENZ
  • CAS: 205754-33-2
  • MF: C14H9ClF3NO3
  • MW: 331.67
  • EINECS:
  • MDL Number:MFCD09840726
  • Synonyms:RAC 8-HYDROXY EFAVIRENZ;8-HydroxyEfavirenz;6-Chloro-4-(cyclopropyl-d4-ethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one;(4S)-6-chloro-4-(2-cyclopropylethynyl)-8-hydroxy-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one;Efavirenz Impurity 11(8-Hydroxy Efavirenz);2H-3,1-Benzoxazin-2-one, 6-chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-, (4S)-;8-Hydroxy EfavirenzQ: What is 8-Hydroxy Efavirenz Q: What is the CAS Number of 8-Hydroxy Efavirenz Q: What is the storage condition of 8-Hydroxy Efavirenz Q: What are the applications of 8-Hydroxy Efavirenz;2H-3,1-Benzoxazin-2-one,6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-, (4S)-
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :144-154°C
Boiling point :373.6±42.0 °C(Predicted)
Density :1?+-.0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Acetonitrile: soluble; DMSO: soluble; Methanol: soluble
form :A solid
pka :7.18±0.40(Predicted)
color :White to off-white

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

8-hydroxy Efavirenz is a major oxidative metabolite of the non-nucleoside reverse transcriptase inhibitor efavirenz . 8-hydroxy Efavirenz is formed when efavirenz is metabolized by the cytochrome P450 (CYP) isoform CYP2B6. It induces apoptosis in rat primary hippocampal neurons and loss of dendritic spines in rat primary hippocampal neuronal cultures when used at a concentration of 0.01 μM.

More related product prices

L 741211 391860-73-4 rac 8-Hydroxy Efavirenz Efavirenz Related Compound B (15 mg) ((S,E)-6-Chloro-4-(2-Cyclopropylvinyl)-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one) rac Methyl Efavirenz 209414-27-7 rac 7-Hydroxy Efavirenz [4-Chloro-2-[(1S)-3-cyclopropyl-1-hydroxy-1-(trifluoromethyl)-2-propynyl)phenyl]carbamic Acid Methyl Ester

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Suppliers and manufacturers

Pharma Affiliates CLEARSYNTH LABS LTD. Pharmaffiliates Analytics and Synthetics P. Ltd Guangzhou PI PI Biotech Inc DC Chemicals Shanghai SuperLan Chemcial Technique Centre Nantong Hanfang Biotechnology Co. , Ltd. Nanjing Shizhou Biology Technology Co.,Ltd TargetMol Chemicals Inc. SHANGHAI ZZBIO CO., LTD.