REVEROMYCIN A
- ₹30558.98
- Product name: REVEROMYCIN A
- CAS: 134615-37-5
- MF: C36H52O11
- MW: 660.79
- EINECS:
- MDL Number:MFCD00912537
- Synonyms:REVEROMYCIN A;ZESGNAJSBDILTB-OXVOKJAASA-N;Butanedioic acid, 1-[(2S,3R,6S,8R,9S)-3-butyl-8-[(2E,4E,6S,7S,8E)-9-carboxy-6-hydroxy-3,7-dimethyl-2,4,8-nonatrien-1-yl]-2-[(1E,3E)-4-carboxy-3-methyl-1,3-butadien-1-yl]-9-methyl-1,7-dioxaspiro[5.5]undec-3-yl] ester
1 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 100μG
- ManufacturerSigma-Aldrich(India)
- Product numberR0654
- Product descriptionReveromycin A solid
- Packaging100μG
- Price₹30558.98
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | R0654 | Reveromycin A solid | 100μG | ₹30558.98 | 2022-06-14 | Buy |
Properties
Boiling point :849.0±65.0 °C(Predicted)
Density :1.21±0.1 g/cm3(Predicted)
storage temp. :−20°C
solubility :DMF: soluble
form :solid
pka :4.36±0.17(Predicted)
color :tan
Density :1.21±0.1 g/cm3(Predicted)
storage temp. :−20°C
solubility :DMF: soluble
form :solid
pka :4.36±0.17(Predicted)
color :tan
Safety Information
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Description
Reveromycin A is the major component of a complex of spiroketal antibiotics isolated from Streptomyces sp. It inhibits the mitogenic activity of epidermal growth factor in Balb/MK cells (IC50 = 0.7 μg/ml), displays antiproliferative activity against human KB and K562 tumor cell lines (IC50s = 1.9 and 1.6 μg/ml, respectively), and demonstrates antifungal activity against C. albicans (MIC = 2 μg/ml at pH 3). Reveromycin A also has been shown to inhibit bone resorption by inducing apoptosis in osteoclasts with an IC50 value of 0.7 μM.More related product prices
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