REVEROMYCIN A
- CAS No.
- 134615-37-5
- Chemical Name:
- REVEROMYCIN A
- Synonyms
- REVEROMYCIN A;ZESGNAJSBDILTB-OXVOKJAASA-N;Butanedioic acid, 1-[(2S,3R,6S,8R,9S)-3-butyl-8-[(2E,4E,6S,7S,8E)-9-carboxy-6-hydroxy-3,7-dimethyl-2,4,8-nonatrien-1-yl]-2-[(1E,3E)-4-carboxy-3-methyl-1,3-butadien-1-yl]-9-methyl-1,7-dioxaspiro[5.5]undec-3-yl] ester
- CBNumber:
- CB4443481
- Molecular Formula:
- C36H52O11
- Molecular Weight:
- 660.79
- MOL File:
- 134615-37-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/5/18 11:31:09
REVEROMYCIN A Chemical Properties,Uses,Production
Uses
Reveromycin A, the dominant analogue of a complex of spiroketals isolated from a Streptomyces sp., is an inhibitor of the mitogenic activity of EGF. Reveromycin A is a G1 phase cell cycle inhibitor, selectively inhibiting isoleucyl-tRNA synthetase. Reveromycin A displays antiproliferative behaviour against human cell lines KB and K562, as well as potent antifungal activity. More recently it has been shown to induce apoptosis in osteoclasts thus inhibiting bone resorption.
REVEROMYCIN A Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 59)Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
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CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
BOC Sciences | 16314854226; +16314854226 | United States | 19743 | 58 | Inquiry |
Alfa Chemistry | +1-5166625404 | United States | 21317 | 58 | Inquiry |
Aladdin Scientific | +1-+1(833)-552-7181 | United States | 52927 | 58 | Inquiry |
TargetMol Chemicals Inc. | 15002134094 | China | 28118 | 58 | Inquiry |
Alfa Chemistry | 1-516-6625404 | United States | 9171 | 60 | Inquiry |
Cayman Chemical Company | (800) 364-9897 | United States | 6618 | 81 | Inquiry |
Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | China | 9708 | 58 | Inquiry |
Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 | China | 4428 | 55 | Inquiry |
Changzhou Xianglong Pharmaceutical Technology Co., LTD | 0519-88910898 18661161657 | China | 9998 | 58 | Inquiry |
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REVEROMYCIN A
ZESGNAJSBDILTB-OXVOKJAASA-N
Butanedioic acid, 1-[(2S,3R,6S,8R,9S)-3-butyl-8-[(2E,4E,6S,7S,8E)-9-carboxy-6-hydroxy-3,7-dimethyl-2,4,8-nonatrien-1-yl]-2-[(1E,3E)-4-carboxy-3-methyl-1,3-butadien-1-yl]-9-methyl-1,7-dioxaspiro[5.5]undec-3-yl] ester
134615-37-5
C36H52O11
BioChemical
Antibiotics
Antibiotics A to Z
Antibiotics N-S
Epidermal Growth Factor Receptor (EGFR)Antibiotics
Interferes with Protein Synthesis
Antibiotics
Antibiotics A to
Antibiotics by Application
Antibiotics N-SAntibiotics
AntifungalAntibiotics
Mechanism of Action
Receptor Tyrosine Kinase Inhibitors
Spectrum of Activity
Antineoplastic and Immunosuppressive AntibioticsReceptor Tyrosine Kinase Biology