REVEROMYCIN D

REVEROMYCIN D Structure
CAS No.
144860-70-8
Chemical Name:
REVEROMYCIN D
Synonyms
REVEROMYCIN D;Butanedioic acid, 1-[(2S,3R,6S,8R,9S)-8-[(2E,4E,6S,7S,8E)-9-carboxy-6-hydroxy-3,7-dimethyl-2,4,8-nonatrien-1-yl]-2-[(1E,3E)-4-carboxy-3-methyl-1,3-butadien-1-yl]-9-methyl-3-pentyl-1,7-dioxaspiro[5.5]undec-3-yl] ester
CBNumber:
CB8173027
Molecular Formula:
C37H54O11
Molecular Weight:
674.82
MOL File:
144860-70-8.mol
MSDS File:
SDS
Modify Date:
2023/5/21 10:59:17

REVEROMYCIN D Properties

Boiling point 855.3±65.0 °C(Predicted)
Density 1.20±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
form White to tan solid.
pka 4.36±0.17(Predicted)

REVEROMYCIN D Chemical Properties,Uses,Production

Description

Reveromycin D is a bacterial metabolite originally isolated from Streptomyces. It inhibits EGF-induced mitogenic activity in Balb/MK cells and has pH-dependent antifungal activity against C. albicans (MICs = 2 and >500 μg/ml at pH 3 and 7.4, respectively). Reveromycin D also inhibits proliferation of KB and K562 cells (IC50s = 1.6 and 1.3 μg/ml, respectively).

Uses

Reveromycin D is the isopentyl analogue and a minor component of the reveromycin complex, isolated from a Streptomyces sp.. Published information on reveromycin D suggests that it is more active than its straight chain analogue, reveromycin C.

REVEROMYCIN D Preparation Products And Raw materials

Raw materials

Preparation Products

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REVEROMYCIN D Butanedioic acid, 1-[(2S,3R,6S,8R,9S)-8-[(2E,4E,6S,7S,8E)-9-carboxy-6-hydroxy-3,7-dimethyl-2,4,8-nonatrien-1-yl]-2-[(1E,3E)-4-carboxy-3-methyl-1,3-butadien-1-yl]-9-methyl-3-pentyl-1,7-dioxaspiro[5.5]undec-3-yl] ester 144860-70-8