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RHEIN-8-GLUCOSIDE

RHEIN-8-GLUCOSIDE Structure
  • ₹0
  • Product name: RHEIN-8-GLUCOSIDE
  • CAS: 34298-86-7
  • MF: C21H18O11
  • MW: 446.36
  • EINECS:
  • MDL Number:MFCD00075898
  • Synonyms:RHEIN-8-GLUCOSIDE;Rhein 8-O-glucoside;Glucorein;8-Glucosidorhein-9-anthrone;5-(beta-D-Glucopyranosyloxy)-9,10-dihydro-4-hydroxy-9,10-dioxo-2-anthracenecarboxylic acid;Rhein-5-O-β-D-glucopyranoside;Rhein-8-O-glucopyranoside;Rhein 8Glucoside,Inhibitor,Rhein 8-Glucoside,Rhein 8 Glucoside,inhibit
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :>245°C (dec.)
Boiling point :854.4±65.0 °C(Predicted)
Density :1.736±0.06 g/cm3(Predicted)
storage temp. :Hygroscopic, Refrigerator, under inert atmosphere
solubility :DMSO (Slightly)
pka :3.19±0.20(Predicted)
form :Solid
color :Yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Rhein 8-Glucoside has been seen to exhibit cytotoxic and DNA-damaging properties towards tumor and normal human cells. In addition it has been shown to be an inhibitor of PTP1B (Human Protein Tyrosine Kinase 1B) in vitro. It is an analog of Rhein (R318500) which is found in the free state and as glucoside in Rheum spp, Polygonaceae (rhubarb) and in Senna leaves. It is a potential antioxidant resource: endophytic fungi from medicinal plants.

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Suppliers and manufacturers

CLEARSYNTH LABS LTD.
Chengdu GLP biotechnology Co Ltd
Chengdu Biopurify Phytochemicals Ltd.
Shaanxi Pioneer Biotech Co., Ltd .
Hubei Ipure Biology Co., Ltd
TargetMol Chemicals Inc.
ShenZhen Trendseen Biological Technology Co.,Ltd.
LEAPCHEM CO., LTD.
Aladdin Scientific Wuhan Huangzhen Biochemical Co., Ltd