Riluzole
- ₹5100 - ₹114008.9
- Product name: Riluzole
- CAS: 1744-22-5
- MF: C8H5F3N2OS
- MW: 234.2
- EINECS:605-724-6
- MDL Number:MFCD00210213
- Synonyms:6-TRIFLUOROMETHOXYBENZOTHIAZOLE-2-YL-AMINE;6-(TRIFLUOROMETHOXY)-1,3-BENZOTHIAZOL-2-AMINE;6-TRIFLUOROMETHOXY-BENZOTHIAZOL-2-YLAMINE;6-trifluoromethoxy-2-aminobenzothiazole;6-(TRIFLUOROMETHOXY)-2-BENZOTHIAZOLAMINE;CBI-BB ZERO/001785;BUTTPARK 13\02-09;2-AMINO-6-(TRIFLUOROMETHOXY)BENZOTHIAZOLE
6 prices
Selected condition:
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 25MG
- 50MG
- 250MG
- 500MG
- 5G
- 25G
- ManufacturerTCI Chemicals (India)
- Product numberA2423
- Product descriptionRiluzole
- Packaging5G
- Price₹5100
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberA2423
- Product descriptionRiluzole
- Packaging25G
- Price₹13600
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberR116
- Product descriptionRiluzole solid
- Packaging25MG
- Price₹10013.13
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number557324
- Product descriptionRiluzole - CAS 1744-22-5 - Calbiochem A cell-permeable benzothiazole compound that potently inhibits glutamate release and blocks Na+ channels.
- Packaging50MG
- Price₹15280
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberR116
- Product descriptionRiluzole solid
- Packaging250MG
- Price₹65848.48
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberR116
- Product descriptionRiluzole solid
- Packaging500MG
- Price₹114008.9
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
TCI Chemicals (India) | A2423 | Riluzole | 5G | ₹5100 | 2022-05-26 | Buy |
TCI Chemicals (India) | A2423 | Riluzole | 25G | ₹13600 | 2022-05-26 | Buy |
Sigma-Aldrich(India) | R116 | Riluzole solid | 25MG | ₹10013.13 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 557324 | Riluzole - CAS 1744-22-5 - Calbiochem A cell-permeable benzothiazole compound that potently inhibits glutamate release and blocks Na+ channels. | 50MG | ₹15280 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | R116 | Riluzole solid | 250MG | ₹65848.48 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | R116 | Riluzole solid | 500MG | ₹114008.9 | 2022-06-14 | Buy |
Properties
Melting point :116-118°C
Boiling point :296.3±50.0 °C(Predicted)
Density :1.572±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥25 mg/mL
form :solid
pka :2.96±0.10(Predicted)
color :white
Merck :14,8223
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
InChIKey :FTALBRSUTCGOEG-UHFFFAOYSA-N
Boiling point :296.3±50.0 °C(Predicted)
Density :1.572±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥25 mg/mL
form :solid
pka :2.96±0.10(Predicted)
color :white
Merck :14,8223
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
InChIKey :FTALBRSUTCGOEG-UHFFFAOYSA-N
Safety Information
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Signal word: | Danger | ||||||||||||||
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Description
Riluzole belongs to the derivative of benzothiazole with neuroprotective, potential anti-depressant and anxiolytic activities, which is used in the treatment of a certain type of nerve disease called amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease). It is effective to delay the onset of ventilator-dependence or tracheostomy in selected patients, slow down the deterioration of this disease and probably prolong survival by approximately two to three months. Besides, studies have proved that riluzole has anti-depressant activity for refractory depression and serves as an anxiolytic in the treatment of obsessive-compulsive disorder and generalized anxiety disorder.However, riluzole does not cure the ALS and reverse nerve damage or muscle weakness. It is believed to function as an inhibitor of a natural substance called glutamate. It helps protect the nerves in the brain and spinal cord from too much of glutamate which may contribute to the nerve damage. Riluzole is available in both tablet and liquid form. The liquid formulation may be more suitable for patients with swallowing difficulties.
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