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ChemicalBook > Product Catalogue >Pharmaceutical intermediates >Bulk Drug Intermediates >(S)-2-Benzylsuccinic acid

(S)-2-Benzylsuccinic acid

(S)-2-Benzylsuccinic acid Structure
  • ₹6200
  • Product name: (S)-2-Benzylsuccinic acid
  • CAS: 3972-36-9
  • MF: C11H12O4
  • MW: 208.21
  • EINECS:609-742-5
  • MDL Number:MFCD00798341
  • Synonyms:(S)-2-BENZYLSUCCINIC ACID;(S)-2-BENZYL-1,4-BUTANEDIOIC ACID;Mitiglinide intermediate 2;Mitiglinide intermediate 8;(S)-2-Benzylsuccinic acid (Mitiglinide);(S)-2-Benzylsuccinic (2S)-2-benzylbutanedioic acid;Butanedioicacid, 2-(phenylmethyl)-, (2S)-
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Brand

  • TCI Chemicals (India)

Package

  • 5G
  • ManufacturerTCI Chemicals (India)
  • Product numberB4142
  • Product description(S)-Benzylsuccinic Acid
  • Packaging5G
  • Price₹6200
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) B4142 (S)-Benzylsuccinic Acid 5G ₹6200 2022-05-26 Buy

Properties

Melting point :164.0 to 168.0 °C
Boiling point :331.4±22.0 °C(Predicted)
Density :1.290±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
form :powder to crystal
pka :3.97±0.10(Predicted)
color :White to Almost white
InChI :InChI=1S/C11H12O4/c12-10(13)7-9(11(14)15)6-8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H,12,13)(H,14,15)/t9-/m0/s1
InChIKey :GTOFKXZQQDSVFH-VIFPVBQESA-N
SMILES :C(O)(=O)[C@@H](CC1=CC=CC=C1)CC(O)=O
CAS DataBase Reference :3972-36-9(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

(S)-2-Benzylsuccinic acid is a widely used compound, which was employed as a key intermediate for hypoglycemic KAD-1229 by means of asymmetric alkylation of N-acylsulta. It can be synthesized by various procedures. The preparation of (S)-2-benzylsuccinic acid from L-phenylalanine is considered to be one of the most clean, efficient and convenient processes. The compound is a common chiral synthesis intermediate.

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