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S-(-)-Carbidopa

S-(-)-Carbidopa Structure
  • ₹9731.68 - ₹28080.05
  • Product name: S-(-)-Carbidopa
  • CAS: 28860-95-9
  • MF: C10H14N2O4
  • MW: 226.23
  • EINECS:657-445-4
  • MDL Number:MFCD00069231
  • Synonyms:[-]-L-α-Hydrazino-3,4-dihydroxy-α-methylhydrocinnamic acid monohydrate;s-(-)-α-hydrazino-3,4-dihydroxy-2-methylbenzenepropanoic acid;CARBIDOPAANHYDROUS;S-(-)-CARBIDOPA,ANHYDROUS;S-(-)-ALPHA-HYDRAZINO-3,4-DIHYDROXY-2-METHYLBENZENEPROPANOIC ACID;S(-)-ALPHA-HYDRAZINO-3,4-DIHYDROXY-ALPHA-METHYLBENZENEPROPANOIC ACID;S-ALPHA-HYDRAZINO-3,4-DIHYDROXY-ALPHA-METHYLBENZENEPROPANOIC ACID;(S)-ALPHA-HYDRAZINO-ALPHA-METHYL-BETA-(3,4-DIHYDROXYPHENYL)PROPIONIC ACID
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 25MG
  • 100MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberC1335
  • Product descriptionS-(−)-Carbidopa ≥98% (TLC), powder
  • Packaging100MG
  • Price₹28080.05
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC1335
  • Product descriptionS-(−)-Carbidopa ≥98% (TLC), powder
  • Packaging25MG
  • Price₹9731.68
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) C1335 S-(−)-Carbidopa ≥98% (TLC), powder 100MG ₹28080.05 2022-06-14 Buy
Sigma-Aldrich(India) C1335 S-(−)-Carbidopa ≥98% (TLC), powder 25MG ₹9731.68 2022-06-14 Buy

Properties

Melting point :203-205° (dec); mp 208°
alpha :D -17.3° (methanol)
Boiling point :367.84°C (rough estimate)
Density :1.2616 (rough estimate)
refractive index :1.5000 (estimate)
storage temp. :-20°C
solubility :DMSO (Slightly), Methanol (Slightly)
form :powder
pka :3.40±0.14(Predicted)
color :White to Off-White
Stability :Unstable in Solution
CAS DataBase Reference :28860-95-9(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

S(-)-Carbidopa is an inhibitor of DDC, the enzyme responsible for conversion of L-DOPA to dopamine. Administration of S(-)-Carbidopa with L-DOPA demonstrates a decrease in the effects associated with rapid conversion of L-DOPA to dopamine. S(-)-Carbidopa is also demonstrated to prolong the elimination half-life of L-DOPA from blood plasma and skeletal muscle.

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