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(S)-MEPHENYTOIN

(S)-MEPHENYTOIN Structure
  • ₹79330 - ₹142740
  • Product name: (S)-MEPHENYTOIN
  • CAS: 70989-04-7
  • MF: C12H14N2O2
  • MW: 218.25
  • EINECS:
  • MDL Number:MFCD00270025
  • Synonyms:(S)-(+)-5-Ethyl-3-methyl-5-phenyl-2,4-imidazolidinedione, (S)-(+)-5-Ethyl-3-methyl-5-phenylhydantoin;(5S)-5-Ethyl-3-methyl-5-phenylhydantoin;(5S)-5β-Ethyl-3-methyl-5-phenylhydantoin;Mephenitoin S;(5S)-5-ethyl-3-methyl-5-phenyl-imidazolidine-2,4-dione;(5S)-5-ethyl-3-methyl-5-phenylimidazolidine-2,4-dione;(S)-(+)-MEPHENYTOIN;(S)-(+)-5-ETHYL-3-METHYL-5-PHENYL-2,4-IMIDAZOLIDINEDIONE
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 10MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberUC175
  • Product description(S)-(+)-Mephenytoin solid, ≥98% (HPLC)
  • Packaging5MG
  • Price₹79330
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberUC175
  • Product description(S)-(+)-Mephenytoin solid, ≥98% (HPLC)
  • Packaging10MG
  • Price₹142740
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) UC175 (S)-(+)-Mephenytoin solid, ≥98% (HPLC) 5MG ₹79330 2022-06-14 Buy
Sigma-Aldrich(India) UC175 (S)-(+)-Mephenytoin solid, ≥98% (HPLC) 10MG ₹142740 2022-06-14 Buy

Properties

Melting point :135-138 °C
Density :1.154±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble
form :solid
pka :8.07±0.70(Predicted)
color :off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

(S)-Mephenytoin is a substrate of the cytochrome P450 (CYP) isoform CYP2C19, also known as mephenytoin 4-hydroxylase. CYP2C19 metabolizes a variety of therapeutic agents, including omeprazole, proguanil, diazepam, propranolol, citalopram, imipramine, and certain barbiturates. Genetic defects in CYP2C19 result in poor metabolism of these compounds, and (S)-mephenytoin can be used to screen for such mutations by assaying its metabolites in urine. (S)-Mephenytoin has anticonvulsant activities.

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