STAUROSPORINE
|
- ₹15400 - ₹155003.18
- Product name: STAUROSPORINE
- CAS: 62996-74-1
- MF: C28H26N4O3
- MW: 466.54
- EINECS:613-127-7
- MDL Number:MFCD18252446
- Synonyms:9,13-Epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one, 2,3,10,11,12,13-hexahydro-10-methoxy-9-methyl-11-(methylamino)-, [9S-(9α,10β,11β,13α)]-;InSolution Staurosporine, Streptomyces sp;Staurosporineinsolution;9,13-Epoxy-1H,9H-diindolo1,2,3-gh:3,2,1-lmpyrrolo3,4-j1,7benzodiazonin-1-one, 2,3,10,11,12,13-hexahydro-10-methoxy-9-methyl-11-(methylamino)-, (9S,10R,11R,13R)-;Staurosporine, Antibiotic AM-2282;(9S,10R,11R,13R)-2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one;Antibiotic 230;CGP 39360
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- Sigma-Aldrich
- Sigma-Aldrich(India)
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- 250μG
- 1MG
- 10MG
- 200μG
- 0.5MG
- 100μG
- 0.1MG
- ManufacturerSigma-Aldrich
- Product numberS5921
- Product descriptionStaurosporine from Streptomyces sp. for molecular biology, ≥95% (HPLC)
- Packaging1MG
- Price₹146256.58
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number569397
- Product descriptionStaurosporine, Streptomyces sp. Staurosporine, CAS 62996-74-, is a cell-permeable, potent, reversible, ATP-competitive inhibitor of protein kinases (IC?? = 7, 20, 1.3, 0.7, & 8.5 nM
- Packaging100μG
- Price₹15400
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number569396
- Product descriptionInSolution Staurosporine, Streptomyces sp. InSolution Staurosporine, Streptomyces sp. CAS 62996-74-1, is provided as a 1 mM (100 μg/214 μl) solution of Staurosporine (Cat. No. 569397) in DMSO
- Packaging100μG
- Price₹21460
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberS4400
- Product descriptionStaurosporine from Streptomyces sp. ≥98% (HPLC), film
- Packaging0.1MG
- Price₹23262.93
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberS5921
- Product descriptionStaurosporine from Streptomyces sp. for molecular biology, ≥95% (HPLC)
- Packaging0.1MG
- Price₹24540.28
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number19-123-M
- Product descriptionStaurosporine Staurosporine Streptomyces is a potent, cell-permeable, reversible, ATP-competitive and broad spectrum inhibitor of protein kinases.
- Packaging200μG
- Price₹30920
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number569397
- Product descriptionStaurosporine, Streptomyces sp. Staurosporine, CAS 62996-74-, is a cell-permeable, potent, reversible, ATP-competitive inhibitor of protein kinases (IC?? = 7, 20, 1.3, 0.7, & 8.5 nM
- Packaging250μG
- Price₹32359.99
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number37095
- Product descriptionStaurosporine VETRANAL?, analytical standard
- Packaging10MG
- Price₹155003.18
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number19-123-M
- Product descriptionStaurosporine Staurosporine Streptomyces is a potent, cell-permeable, reversible, ATP-competitive and broad spectrum inhibitor of protein kinases.
- Packaging1MG
- Price₹69100.01
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberS4400
- Product descriptionStaurosporine from Streptomyces sp. ≥98% (HPLC), film
- Packaging0.5MG
- Price₹77701.85
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberS5921
- Product descriptionStaurosporine from Streptomyces sp. for molecular biology, ≥95% (HPLC)
- Packaging0.5MG
- Price₹82118.45
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number569397
- Product descriptionStaurosporine, Streptomyces sp. Staurosporine, CAS 62996-74-, is a cell-permeable, potent, reversible, ATP-competitive inhibitor of protein kinases (IC?? = 7, 20, 1.3, 0.7, & 8.5 nM
- Packaging1MG
- Price₹117280
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberS4400
- Product descriptionStaurosporine from Streptomyces sp. ≥98% (HPLC), film
- Packaging1MG
- Price₹140097.15
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberS5921
- Product descriptionStaurosporine from Streptomyces sp. for molecular biology, ≥95% (HPLC)
- Packaging1MG
- Price₹146256.58
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich | S5921 | Staurosporine from Streptomyces sp. for molecular biology, ≥95% (HPLC) | 1MG | ₹146256.58 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 569397 | Staurosporine, Streptomyces sp. Staurosporine, CAS 62996-74-, is a cell-permeable, potent, reversible, ATP-competitive inhibitor of protein kinases (IC?? = 7, 20, 1.3, 0.7, & 8.5 nM | 100μG | ₹15400 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 569396 | InSolution Staurosporine, Streptomyces sp. InSolution Staurosporine, Streptomyces sp. CAS 62996-74-1, is provided as a 1 mM (100 μg/214 μl) solution of Staurosporine (Cat. No. 569397) in DMSO | 100μG | ₹21460 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | S4400 | Staurosporine from Streptomyces sp. ≥98% (HPLC), film | 0.1MG | ₹23262.93 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | S5921 | Staurosporine from Streptomyces sp. for molecular biology, ≥95% (HPLC) | 0.1MG | ₹24540.28 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 19-123-M | Staurosporine Staurosporine Streptomyces is a potent, cell-permeable, reversible, ATP-competitive and broad spectrum inhibitor of protein kinases. | 200μG | ₹30920 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 569397 | Staurosporine, Streptomyces sp. Staurosporine, CAS 62996-74-, is a cell-permeable, potent, reversible, ATP-competitive inhibitor of protein kinases (IC?? = 7, 20, 1.3, 0.7, & 8.5 nM | 250μG | ₹32359.99 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 37095 | Staurosporine VETRANAL?, analytical standard | 10MG | ₹155003.18 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 19-123-M | Staurosporine Staurosporine Streptomyces is a potent, cell-permeable, reversible, ATP-competitive and broad spectrum inhibitor of protein kinases. | 1MG | ₹69100.01 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | S4400 | Staurosporine from Streptomyces sp. ≥98% (HPLC), film | 0.5MG | ₹77701.85 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | S5921 | Staurosporine from Streptomyces sp. for molecular biology, ≥95% (HPLC) | 0.5MG | ₹82118.45 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 569397 | Staurosporine, Streptomyces sp. Staurosporine, CAS 62996-74-, is a cell-permeable, potent, reversible, ATP-competitive inhibitor of protein kinases (IC?? = 7, 20, 1.3, 0.7, & 8.5 nM | 1MG | ₹117280 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | S4400 | Staurosporine from Streptomyces sp. ≥98% (HPLC), film | 1MG | ₹140097.15 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | S5921 | Staurosporine from Streptomyces sp. for molecular biology, ≥95% (HPLC) | 1MG | ₹146256.58 | 2022-06-14 | Buy |
Properties
Melting point :270°C
alpha :D25 +35.0° (c = 1 in methanol); D22 +56.1° (c = 0.14 in methanol)
Boiling point :677.5±55.0 °C(Predicted)
Density :1.56±0.1 g/cm3(Predicted)
RTECS :KD5084000
storage temp. :2-8°C
solubility :DMSO: soluble
form :White to pale yellow solid
pka :14.25±0.70(Predicted)
color :Off white to pale yellow
Water Solubility :Soluble in DMSO or ethanol.Soluble in dimethyl sulfoxide , dimethyl formamide, ethyl acetate, hot acetone and ethanol. Slightly soluble in chloroform and methanol. Insoluble in water.
BRN :1060573
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 4 months.
InChIKey :HKSZLNNOFSGOKW-WIFUGMKFSA-N
CAS DataBase Reference :62996-74-1
alpha :D25 +35.0° (c = 1 in methanol); D22 +56.1° (c = 0.14 in methanol)
Boiling point :677.5±55.0 °C(Predicted)
Density :1.56±0.1 g/cm3(Predicted)
RTECS :KD5084000
storage temp. :2-8°C
solubility :DMSO: soluble
form :White to pale yellow solid
pka :14.25±0.70(Predicted)
color :Off white to pale yellow
Water Solubility :Soluble in DMSO or ethanol.Soluble in dimethyl sulfoxide , dimethyl formamide, ethyl acetate, hot acetone and ethanol. Slightly soluble in chloroform and methanol. Insoluble in water.
BRN :1060573
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 4 months.
InChIKey :HKSZLNNOFSGOKW-WIFUGMKFSA-N
CAS DataBase Reference :62996-74-1
Safety Information
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Description
Staurosporine (Stsp) is potent inhibitor of protein kinase C (PKC) from rat brain, exhibiting an IC50 value of 2.7 nM. It inhibits rat recombinant PKC-α approximately 100- and 1,000-fold better than PKC-δ and PKC-ζ, respectively. However, Stsp is non-selective in that it also inhibits the activity of a variety of other protein kinases, not only PKC isoforms. The biological effects of Stsp include cytotoxicity, relaxation of smooth muscle, and regulation of eNOS gene expression.Related product price
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