Sancycline
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- ₹0
- Product name: Sancycline
- CAS: 808-26-4
- MF: C21H22N2O7
- MW: 414.41
- EINECS:
- MDL Number:MFCD00864992
- Synonyms:SANCYCLINE;(4S,4aS,5aR,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1-11-dioxo-2-naphthacenecarboxamide;6-Demethyl-6-deoxytetracycline;Bonomycin;GS 2147;Norcycline;(4S,4aS,5aR,12aS)-4-(Dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-2-naphthacenecarboxamide;NSC-51812
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Properties
Melting point :224-2280C (dec)
Boiling point :750.9±60.0 °C(Predicted)
Density :1.61±0.1 g/cm3(Predicted)
storage temp. :Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility :Aqueous Acid (Slightly), Chloroform (Slightly), Methanol (Slightly)
form :Solid
pka :4.50±1.00(Predicted)
color :Beige to Dark Beige
Stability :Hygroscopic
CAS DataBase Reference :808-26-4
Boiling point :750.9±60.0 °C(Predicted)
Density :1.61±0.1 g/cm3(Predicted)
storage temp. :Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility :Aqueous Acid (Slightly), Chloroform (Slightly), Methanol (Slightly)
form :Solid
pka :4.50±1.00(Predicted)
color :Beige to Dark Beige
Stability :Hygroscopic
CAS DataBase Reference :808-26-4
Safety Information
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Description
Sancycline is a semisynthetic tetracycline antibiotic that is more active than tetracycline against 339 strains of anaerobic bacteria (average MIC90s = 1 and 32 μg/ml, respectively). Sancycline is active against tetracycline-resistant E. coli, S. aureus, and E. faecalis strains with MICs ranging from 0.06 to 1 μg/ml. In vivo, sancycline is active against S. aureus in mice with ED50 values of 0.46 and 0.6 mg/kg for intravenous and subcutaneous administration, respectively.More related product prices
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