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ChemicalBook > Product Catalogue >API >Nervous system drugs >Antidepressants, Antimanics drugs >Sertraline hydrochloride

Sertraline hydrochloride

Sertraline hydrochloride Structure
  • ₹4708.2 - ₹63802.55
  • Product name: Sertraline hydrochloride
  • CAS: 79559-97-0
  • MF: C17H18Cl3N
  • MW: 342.69
  • EINECS:616-702-0
  • MDL Number:MFCD00895772
  • Synonyms:(1S,4S)-4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-N-METHYL-1-NAPTHALENAMINE HYDROCHLORIDE;(1S,4S)-1-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-4-(METHYLAMINO)NAPHTHALENE HYDROCHLORIDE;SERTRALINE HCL FORM I;SERTRALINE HCL FORM II;SERTRALINE HYDROCHLORIDE;Rac-cis-Sertraline-13C-d3 HCl;1-NaphthalenaMine,4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-Methyl-, hydrochloride (1:1),(1S,4S)-;CP-51974-1 HCl
Price6 Properties Safety Information Description
6 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • 200MG
  • 1G
  • 1ML
  • 5G
  • ManufacturerTCI Chemicals (India)
  • Product numberS0507
  • Product descriptionSertraline Hydrochloride
  • Packaging1G
  • Price₹6100
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberS0507
  • Product descriptionSertraline Hydrochloride
  • Packaging5G
  • Price₹14500
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberS-021
  • Product descriptionSertraline hydrochloride solution 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant?
  • Packaging1ML
  • Price₹4708.2
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberS6319
  • Product descriptionSertraline hydrochloride ≥98% (HPLC)
  • Packaging10MG
  • Price₹14224.05
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR2535
  • Product descriptionSertraline hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging200MG
  • Price₹39792.7
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberS6319
  • Product descriptionSertraline hydrochloride ≥98% (HPLC)
  • Packaging50MG
  • Price₹63802.55
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) S0507 Sertraline Hydrochloride 1G ₹6100 2022-05-26 Buy
TCI Chemicals (India) S0507 Sertraline Hydrochloride 5G ₹14500 2022-05-26 Buy
Sigma-Aldrich(India) S-021 Sertraline hydrochloride solution 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant? 1ML ₹4708.2 2022-06-14 Buy
Sigma-Aldrich(India) S6319 Sertraline hydrochloride ≥98% (HPLC) 10MG ₹14224.05 2022-06-14 Buy
Sigma-Aldrich(India) PHR2535 Sertraline hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material 200MG ₹39792.7 2022-06-14 Buy
Sigma-Aldrich(India) S6319 Sertraline hydrochloride ≥98% (HPLC) 50MG ₹63802.55 2022-06-14 Buy

Properties

Melting point :246-249°C
alpha :D23 +37.9° (c = 2 in methanol)
Density :1.37
Flash point :9℃
storage temp. :2-8°C
solubility :DMSO: ~26 mg/mL
form :solid
pka :pKa (water): 9.48 ± 0.04; pKa (methanol:water, 40:60 v/v): 8.6; pKa (ethanol:water, 1:1 v/v): 8.5(at 25℃)
color :white
Merck :14,8467
Stability :Store in Freezer
CAS DataBase Reference :79559-97-0(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H400 Very toxic to aquatic life Hazardous to the aquatic environment, acute hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P273 Avoid release to the environment.

Description

Sertraline is the hydrochloride form of sertraliine. Sertraline belongs to the selective serotonin reuptake inhibitor (SSRI) class antidepressant drug. Sertraline is indicated for the treatment of major depressive disorder in adults as well as obsessive-compulsive disorder, post-traumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD), panic disorder and social anxiety disorder occurring in both adults and children. Its exact mechanism of action is still not fully understand. But it is indicated that this drug can selectively inhibit the reuptake of serotonin at the presynaptic membrane, increasing serotonin levels in the synapses and enhancing serotonergic neurotransmission. This effect seems to be related to the antidepressant effect of sertraliine.

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Suppliers and manufacturers

Lofty labs Aurobindo Pharma Limited Cipla Ltd Chemeca Drugs Private Limited (Vegesna Laboratories Pvt Ltd) Basic Pharma Life Science Pvt Ltd Lee Pharma Ltd Hetero Drugs Limited Sun Pharmaceutical Industries Ltd KRS Pharmaceuticals Pvt. Ltd. Nosch Labs Pvt Ltd