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ChemicalBook > Product Catalogue >API >Nervous system drugs >Antipsychotics >Tandospirone

Tandospirone

Tandospirone Structure
  • ₹15018.3 - ₹55932.9
  • Product name: Tandospirone
  • CAS: 87760-53-0
  • MF: C21H29N5O2
  • MW: 383.49
  • EINECS:
  • MDL Number:MFCD00904852
  • Synonyms:TANDOSPIRONE;4,7-Methano-1H-isoindole-1,3(2H)-dione, hexahydro-2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-, (3aa,4b,7b,7aa)-;4,7-Methano-1H-isoindole-1,3(2H)-dione, hexahydro-2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-, (3aR,4S,7R,7aS)-rel- (9CI);(3αα,4β,7β,7αα)-Hexahydro-2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-4,7-methano-1H-isoindole-1,3(2H)-dione;Sediel;Tandospirone [inn:ban];(3aR,4S,7R,7aS)-rel-Hexahydro-2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-4,7-methano-1H-isoindole-1,3(2H)-dionehydrochloride;Tandospirone hydrochloride
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberT6704
  • Product descriptionTandospirone ≥98% (HPLC)
  • Packaging5MG
  • Price₹15018.3
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT6704
  • Product descriptionTandospirone ≥98% (HPLC)
  • Packaging25MG
  • Price₹55932.9
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) T6704 Tandospirone ≥98% (HPLC) 5MG ₹15018.3 2022-06-14 Buy
Sigma-Aldrich(India) T6704 Tandospirone ≥98% (HPLC) 25MG ₹55932.9 2022-06-14 Buy

Properties

Melting point :112-113.5°
Boiling point :613.9±65.0 °C(Predicted)
Density :1.239±0.06 g/cm3(Predicted)
storage temp. :Store at +4°C
solubility :DMSO: soluble38mg/mL
pka :7.71±0.10(Predicted)
form :Solid
color :White to Off-White

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Tandospirone hydrochloride is a SR-1A partial agonist (Ki = 27 nM) that displays selectivity over SR-2, SR-1C, α1, α2, D1 and D2 receptors (Ki values ranging from 1300-41000 nM). Tandospirone hydrochloride is inactive at serotonin uptake sites, SR-1B, β-adrenergic, muscarinic and benzodiazepine receptors. It displays anxiolytic activity.

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