TETRODOTOXIN
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- Product name: TETRODOTOXIN
- CAS: 4368-28-9
- MF: C11H17N3O8
- MW: 319.27
- EINECS:224-458-8
- MDL Number:MFCD00213719
- Synonyms:TETRODOTOXIN WITHOUT CITRATE BUFFER;TETRODOTOXIN WITH CITRATE BUFFER;Tetrodotoxin, citrate free;5,9:7,10a-Dimethano-10aH-1,3dioxocino6,5-dpyrimidine-4,7,10,11,12-pentol, 2-amino-1,4,4a,5,9,10-hexahydro-12-(hydroxymethyl)-, (4R,4aR,5R,7S,9S,10S,10aR,11S,12S)-;PUFFERFISHTOXIN;PUFFERFISHPOISONING;Globefish toxin;Fugu poison, Maculotoxin, Tarichatoxin, TTX
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Properties
Melting point :280 °C (decomp)
alpha :D25 -8.64° (c = 8.55 in dil acetic acid)
Boiling point :458.31°C (rough estimate)
Density :1.3768 (rough estimate)
refractive index :1.5700 (estimate)
storage temp. :2-8°C
solubility :H2O: stable at pH 4-5 if stored frozensoluble
form :powder
pka :8.76 (water); 9.4 (50% alc)
color :white
Merck :13,9318
Stability :Acid Sensitive, Hygroscopic
CAS DataBase Reference :4368-28-9(CAS DataBase Reference)
EPA Substance Registry System :Tetrodotoxin (4368-28-9)
alpha :D25 -8.64° (c = 8.55 in dil acetic acid)
Boiling point :458.31°C (rough estimate)
Density :1.3768 (rough estimate)
refractive index :1.5700 (estimate)
storage temp. :2-8°C
solubility :H2O: stable at pH 4-5 if stored frozensoluble
form :powder
pka :8.76 (water); 9.4 (50% alc)
color :white
Merck :13,9318
Stability :Acid Sensitive, Hygroscopic
CAS DataBase Reference :4368-28-9(CAS DataBase Reference)
EPA Substance Registry System :Tetrodotoxin (4368-28-9)
Safety Information
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Description
Tetraodotoxin is a kind of extremely potent toxin which exists in the liver and sex organs of some fishes including pufferfish, porcupine fish, ocean sunfish, and toadfish as well as some kind of amphibian, octopus and shellfish species. It is also produced by some bacteria such as Pseudomonas and Vibrio. Tetraodotoxin is extremely toxic to human, interfering with the transmission of signals of nerves to muscles and further causing paralysis of the body muscle. It can be fatal in some cases. Its mechanism of action is inhibiting the firing of action potentials in nerves through binding to the voltage-gated sodium channels in nerve cell membrane and blocking the passages of sodium ions into the nerve cell. People should wear proper protective equipment upon operations and should be subject to proper treatment upon suffering from it. However, it has been under investigation on the treatment of chronic and breakthrough pain in advanced cancer patients.More related product prices
Potassium cyanate TETRODOTOXIN 115-70-8 1,4-Cyclohexanedimethanol 4-(2-AMINOETHYL)TETRAHYDROPYRANRelated product price
- Potassium cyanate
₹1287-23382 - 115-70-8
₹1800-6300 - 1,4-Cyclohexanedimethanol
₹1603-34596.7
Suppliers and manufacturers
CLEARSYNTH LABS LTD.
Hangzhou FandaChem Co.,Ltd.
CONIER CHEM AND PHARMA LIMITED
Neostar United (Changzhou) Industrial Co., Ltd.
Hefei TNJ Chemical Industry Co.,Ltd.
Dorne Chemical Technology co. LTD
Dayang Chem (Hangzhou) Co.,Ltd.
LEAP CHEM CO., LTD.
PT CHEM GROUP LIMITED
