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ChemicalBook > Product Catalogue >Biochemical Engineering >Plant extracts >Tanshinone IIA

Tanshinone IIA

Tanshinone IIA Structure
  • ₹5000 - ₹35776.63
  • Product name: Tanshinone IIA
  • CAS: 568-72-9
  • MF: C19H18O3
  • MW: 294.34
  • EINECS:
  • MDL Number:MFCD00238692
  • Synonyms:AKOS NCG1-0066;3,8,8-TRIMETHYL-8,9,10,11-TETRAHYDROPHENANTHRO[1,2-B]FURAN-1,2-DIONE;TANSHINONE IIA 98+%;1,6,6-TRIMETHYL-6,7,8,9-TETRAHYDRO-PHENANTHRO[1,2-B]FURAN-10,11-DIONE;TANSHINONE IIA;TANSHINONES IIA;tanshiones ;Tanshionesiia
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 5MG
  • 10MG
  • 25MG
  • 50MG
  • ManufacturerTCI Chemicals (India)
  • Product numberT2987
  • Product descriptionTanshinone IIA
  • Packaging10MG
  • Price₹5000
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberT2987
  • Product descriptionTanshinone IIA
  • Packaging50MG
  • Price₹18200
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT4952
  • Product descriptionTanshinone IIA ≥97% (HPLC)
  • Packaging5MG
  • Price₹10013.13
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number51704
  • Product descriptionTanshinone IIA analytical standard
  • Packaging10MG
  • Price₹14148.28
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT4952
  • Product descriptionTanshinone IIA ≥97% (HPLC)
  • Packaging25MG
  • Price₹35776.63
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) T2987 Tanshinone IIA 10MG ₹5000 2022-05-26 Buy
TCI Chemicals (India) T2987 Tanshinone IIA 50MG ₹18200 2022-05-26 Buy
Sigma-Aldrich(India) T4952 Tanshinone IIA ≥97% (HPLC) 5MG ₹10013.13 2022-06-14 Buy
Sigma-Aldrich(India) 51704 Tanshinone IIA analytical standard 10MG ₹14148.28 2022-06-14 Buy
Sigma-Aldrich(India) T4952 Tanshinone IIA ≥97% (HPLC) 25MG ₹35776.63 2022-06-14 Buy

Properties

Melting point :196.0 to 200.0 °C
Boiling point :480.7±44.0 °C(Predicted)
Density :1.209±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :methanol: soluble5mg/mL, clear, red-orange to red
form :powder, red
color :Orange
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChIKey :HYXITZLLTYIPOF-UHFFFAOYSA-N
LogP :4.925 (est)
CAS DataBase Reference :568-72-9(CAS DataBase Reference)

Safety Information

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Description

Tanshinone IIA (TSA) is a major lipophilic component of extracts from the root of S. miltiorrhiza, used widely in Chinese herbal medicine. It has anti-inflammatory activity, inhibiting production of TNF-α, IL-1β, IL-6, NO, INFγ, and expression of iNOS, and IL-12. It blocks human aortic smooth muscle cell migration, inhibits MMP-9 activity, and interferes with PI3K/Akt and ERK1/2 signaling pathways. It is cytotoxic to various cancer cells including A549 lung cancer cells and leukemia cells.Reduction of TSA by NAD(P)H:quinone oxidoreductase (NQO1) generates an unstable intermediate resulting in reactive oxygenase species-mediated apoptotic cell death.

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