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ChemicalBook > Product Catalogue >Chemical Reagents >Organic reagents >Azo, diazo compound >Thiazolyl Blue

Thiazolyl Blue

Thiazolyl Blue Structure
  • ₹531 - ₹106016.1
  • Product name: Thiazolyl Blue
  • CAS: 298-93-1
  • MF: C18H16BrN5S
  • MW: 414.32
  • EINECS:206-069-5
  • MDL Number:MFCD00011964
  • Synonyms:Thiazolyl Blue Tetrazolium Bromide Vetec(TM) reagent grade, 98%;ACRYL/BIS 29:1 PREMIXED PWD ULTRA PURE;3-(4,5-Dimethyl-2-Thiazolyl)-2,5-Diphenyl;3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyl-2,3-dihydro-1H-tetrazol-3-ium bromide;2-(4,5-Dimethylthiazol-2-yl)-3,5-diphenyl-2,3-dihydro-1H-tetrazol-3-ium bromide;2,5-diphenyl-3-(4,5-dimethylthiazol-2-yl)-2h-tetrazolium Bromide;2,5-diphenyl-3-(4,5-dimethylthiazol-2-yl)tetrazolium Bromide;2-(4,5-dimethylthiazol-2-yl)-3,5-diphenyl-2htetrazolium Bromide
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  • TCI Chemicals (India)
  • Sigma-Aldrich(India)
  • SRL
  • ottokemi

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  • 1G
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  • ManufacturerTCI Chemicals (India)
  • Product numberM3297
  • Product descriptionMTT [for Biochemical Research]
  • Packaging200MG
  • Price₹2900
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberD0801
  • Product description3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyltetrazolium Bromide
  • Packaging1G
  • Price₹5000
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberM3297
  • Product descriptionMTT [for Biochemical Research]
  • Packaging1G
  • Price₹8700
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberD0801
  • Product description3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyltetrazolium Bromide
  • Packaging5G
  • Price₹13500
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberM2128
  • Product descriptionThiazolyl Blue Tetrazolium Bromide 98%
  • Packaging100MG
  • Price₹3663
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberM5655
  • Product descriptionThiazolyl Blue Tetrazolium Bromide powder, BioReagent, suitable for cell culture, suitable for insect cell culture, ≥97.5% (HPLC)
  • Packaging100MG
  • Price₹4872.9
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberM2128
  • Product descriptionThiazolyl Blue Tetrazolium Bromide 98%
  • Packaging250MG
  • Price₹5672.1
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product numberM2128
  • Product descriptionThiazolyl Blue Tetrazolium Bromide 98%
  • Packaging500MG
  • Price₹9002.1
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product number475989
  • Product descriptionMTT - CAS 298-93-1 - Calbiochem Membrane-permeable yellow dye that is reduced by mitochondrial reductases in living cells to form the dark blue product, MTT-formazan.
  • Packaging1G
  • Price₹10420
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberM2128
  • Product descriptionThiazolyl Blue Tetrazolium Bromide 98%
  • Packaging5G
  • Price₹10722.6
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberM5655
  • Product descriptionThiazolyl Blue Tetrazolium Bromide powder, BioReagent, suitable for cell culture, suitable for insect cell culture, ≥97.5% (HPLC)
  • Packaging500MG
  • Price₹11277.6
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberM2128
  • Product descriptionThiazolyl Blue Tetrazolium Bromide 98%
  • Packaging1G
  • Price₹15318
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberM5655
  • Product descriptionThiazolyl Blue Tetrazolium Bromide powder, BioReagent, suitable for cell culture, suitable for insect cell culture, ≥97.5% (HPLC)
  • Packaging1G
  • Price₹18725.7
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number475989
  • Product descriptionMTT - CAS 298-93-1 - Calbiochem Membrane-permeable yellow dye that is reduced by mitochondrial reductases in living cells to form the dark blue product, MTT-formazan.
  • Packaging10G
  • Price₹54320
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberM5655
  • Product descriptionThiazolyl Blue Tetrazolium Bromide powder, BioReagent, suitable for cell culture, suitable for insect cell culture, ≥97.5% (HPLC)
  • Packaging5X1G
  • Price₹67732.2
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberM2128
  • Product descriptionThiazolyl Blue Tetrazolium Bromide 98%
  • Packaging10G
  • Price₹106016.1
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) M3297 MTT [for Biochemical Research] 200MG ₹2900 2022-05-26 Buy
TCI Chemicals (India) D0801 3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyltetrazolium Bromide 1G ₹5000 2022-05-26 Buy
TCI Chemicals (India) M3297 MTT [for Biochemical Research] 1G ₹8700 2022-05-26 Buy
TCI Chemicals (India) D0801 3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyltetrazolium Bromide 5G ₹13500 2022-05-26 Buy
Sigma-Aldrich(India) M2128 Thiazolyl Blue Tetrazolium Bromide 98% 100MG ₹3663 2022-06-14 Buy
Sigma-Aldrich(India) M5655 Thiazolyl Blue Tetrazolium Bromide powder, BioReagent, suitable for cell culture, suitable for insect cell culture, ≥97.5% (HPLC) 100MG ₹4872.9 2022-06-14 Buy
Sigma-Aldrich(India) M2128 Thiazolyl Blue Tetrazolium Bromide 98% 250MG ₹5672.1 2022-06-14 Buy
Sigma-Aldrich(India) M2128 Thiazolyl Blue Tetrazolium Bromide 98% 500MG ₹9002.1 2022-06-14 Buy
Sigma-Aldrich(India) 475989 MTT - CAS 298-93-1 - Calbiochem Membrane-permeable yellow dye that is reduced by mitochondrial reductases in living cells to form the dark blue product, MTT-formazan. 1G ₹10420 2022-06-14 Buy
Sigma-Aldrich(India) M2128 Thiazolyl Blue Tetrazolium Bromide 98% 5G ₹10722.6 2022-06-14 Buy
Sigma-Aldrich(India) M5655 Thiazolyl Blue Tetrazolium Bromide powder, BioReagent, suitable for cell culture, suitable for insect cell culture, ≥97.5% (HPLC) 500MG ₹11277.6 2022-06-14 Buy
Sigma-Aldrich(India) M2128 Thiazolyl Blue Tetrazolium Bromide 98% 1G ₹15318 2022-06-14 Buy
Sigma-Aldrich(India) M5655 Thiazolyl Blue Tetrazolium Bromide powder, BioReagent, suitable for cell culture, suitable for insect cell culture, ≥97.5% (HPLC) 1G ₹18725.7 2022-06-14 Buy
Sigma-Aldrich(India) 475989 MTT - CAS 298-93-1 - Calbiochem Membrane-permeable yellow dye that is reduced by mitochondrial reductases in living cells to form the dark blue product, MTT-formazan. 10G ₹54320 2022-06-14 Buy
Sigma-Aldrich(India) M5655 Thiazolyl Blue Tetrazolium Bromide powder, BioReagent, suitable for cell culture, suitable for insect cell culture, ≥97.5% (HPLC) 5X1G ₹67732.2 2022-06-14 Buy
Sigma-Aldrich(India) M2128 Thiazolyl Blue Tetrazolium Bromide 98% 10G ₹106016.1 2022-06-14 Buy

Properties

Melting point :195 °C (dec.) (lit.)
Density :1.4886 (estimate)
storage temp. :2-8°C
solubility :methanol: 5 mg/mL, clear
form :powder
color :Yellow to orange
Water Solubility :Slightly soluble.Clear yellow solution at 5mg in 1ml of water on vortexing
Sensitive :Light Sensitive
λmax :378 nm, 242 nm
BRN :3825277
Stability :Hygroscopic
Biological Applications :Cell viability assay; microbial growth assays; DNA quantification assays; tissue viability assays; detecting enzymes; measuring membrane potential; treating Alzheimer’s disease,asthma,cancer
InChIKey :AZKSAVLVSZKNRD-UHFFFAOYSA-M
CAS DataBase Reference :298-93-1(CAS DataBase Reference)
EPA Substance Registry System :2H-Tetrazolium, 2-(4,5-dimethyl-2-thiazolyl)-3,5-diphenyl-, bromide (298-93-1)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Thiazolyl Blue (MTT, Tetrazolium bromide, Methylthiazolyldiphenyl-tetrazolium bromide, Methylthialazole Tetrazolium) is a cell-permeable and positively charged colorimetric agent that is widely used to detect reductive metabolism in cells and to measure cell proliferation, cytotoxicity, and apoptosis. It is used as a direct indicator of cytotoxicity (such as for screening cancer drugs) and apoptosis. Thiazolyl Blue (MTT) is reduced from yellow color to purple formazan in living cells. As an electron acceptor, it is utilized for studying nicotinamide adenine dinucleotide phosphate (NADP)-dependent dehydrogenases.

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