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ChemicalBook > Product Catalogue >Biochemical Engineering >Enzymes And Coenzymes drugs >Thrombin

Thrombin

Thrombin Structure
  • ₹5361.3 - ₹5405455.8
  • Product name: Thrombin
  • CAS: 9002-04-4
  • MF: NULL
  • MW: 0
  • EINECS:232-648-7
  • MDL Number:MFCD00166053
  • Synonyms:Blood coagulation factor IIa;Thrombin from human plasma,Factor IIa;Thrombin from murine plasma,Factor IIa;Thrombin from bovine plasma,Factor IIa;THROMBIN, BOVINE;ThroMbin froM bovine plasMa 1000 units/Mg protein lyophil.;COAGULATION FACTOR IIA;EC 3.4.21.5
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  • Sigma-Aldrich
  • Sigma-Aldrich(India)

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  • ManufacturerSigma-Aldrich
  • Product number604980
  • Product descriptionThrombin, Bovine, High Activity
  • Packaging100U
  • Price₹13610
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number604980
  • Product descriptionThrombin, Bovine, High Activity
  • Packaging500U
  • Price₹38080
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT7326
  • Product descriptionThrombin from bovine plasma ≥60?NIH units/mg protein (biuret)
  • Packaging1000UNITS
  • Price₹5361.3
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT4648
  • Product descriptionThrombin from bovine plasma lyophilized powder, 40-300?NIH units/mg protein (biuret)
  • Packaging1000UNITS
  • Price₹6471.3
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT6634
  • Product descriptionThrombin from bovine plasma lyophilized powder, 600-2,000?NIH units/mg protein (biuret)
  • Packaging100UNITS
  • Price₹10234.2
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT7513
  • Product descriptionThrombin from bovine plasma lyophilized powder, ≥2,000?NIH units/mg protein (E1%/280 = 19.5)
  • Packaging50UNITS
  • Price₹11877
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number605195
  • Product descriptionThrombin, Human Plasma, High Activity
  • Packaging100U
  • Price₹12230
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT7009
  • Product descriptionThrombin from human plasma lyophilized powder, ≥1,000?NIH units/mg protein (E1%/280, 18.3)
  • Packaging100UNITS
  • Price₹12287.7
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT6884
  • Product descriptionThrombin from human plasma lyophilized powder, ≥2,000?NIH units/mg protein (E1%/280, 18.3)
  • Packaging5000UNITS
  • Price₹297058.2
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSRE0003
  • Product descriptionThrombin from bovine plasma Suitable for manufacturing of diagnostic kits and reagents
  • Packaging100000UNITS
  • Price₹307159.2
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSRE0003
  • Product descriptionThrombin from bovine plasma Suitable for manufacturing of diagnostic kits and reagents
  • Packaging250000UNITS
  • Price₹676789.2
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSRE0003
  • Product descriptionThrombin from bovine plasma Suitable for manufacturing of diagnostic kits and reagents
  • Packaging750000UNITS
  • Price₹1957718.1
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSRE0003
  • Product descriptionThrombin from bovine plasma Suitable for manufacturing of diagnostic kits and reagents
  • Packaging70MU
  • Price₹3153199.2
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSRE0003
  • Product descriptionThrombin from bovine plasma Suitable for manufacturing of diagnostic kits and reagents
  • Packaging120MU
  • Price₹5405455.8
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT6884
  • Product descriptionThrombin from human plasma lyophilized powder, ≥2,000?NIH units/mg protein (E1%/280, 18.3)
  • Packaging1000UNITS
  • Price₹77222.7
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT1063
  • Product descriptionThrombin from human plasma lyophilized powder, ≥2800?NIH units/mg protein (E1%/280, 18.3)
  • Packaging1000UNITS
  • Price₹82728.3
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich 604980 Thrombin, Bovine, High Activity 100U ₹13610 2022-06-14 Buy
Sigma-Aldrich 604980 Thrombin, Bovine, High Activity 500U ₹38080 2022-06-14 Buy
Sigma-Aldrich(India) T7326 Thrombin from bovine plasma ≥60?NIH units/mg protein (biuret) 1000UNITS ₹5361.3 2022-06-14 Buy
Sigma-Aldrich(India) T4648 Thrombin from bovine plasma lyophilized powder, 40-300?NIH units/mg protein (biuret) 1000UNITS ₹6471.3 2022-06-14 Buy
Sigma-Aldrich(India) T6634 Thrombin from bovine plasma lyophilized powder, 600-2,000?NIH units/mg protein (biuret) 100UNITS ₹10234.2 2022-06-14 Buy
Sigma-Aldrich(India) T7513 Thrombin from bovine plasma lyophilized powder, ≥2,000?NIH units/mg protein (E1%/280 = 19.5) 50UNITS ₹11877 2022-06-14 Buy
Sigma-Aldrich(India) 605195 Thrombin, Human Plasma, High Activity 100U ₹12230 2022-06-14 Buy
Sigma-Aldrich(India) T7009 Thrombin from human plasma lyophilized powder, ≥1,000?NIH units/mg protein (E1%/280, 18.3) 100UNITS ₹12287.7 2022-06-14 Buy
Sigma-Aldrich(India) T6884 Thrombin from human plasma lyophilized powder, ≥2,000?NIH units/mg protein (E1%/280, 18.3) 5000UNITS ₹297058.2 2022-06-14 Buy
Sigma-Aldrich(India) SRE0003 Thrombin from bovine plasma Suitable for manufacturing of diagnostic kits and reagents 100000UNITS ₹307159.2 2022-06-14 Buy
Sigma-Aldrich(India) SRE0003 Thrombin from bovine plasma Suitable for manufacturing of diagnostic kits and reagents 250000UNITS ₹676789.2 2022-06-14 Buy
Sigma-Aldrich(India) SRE0003 Thrombin from bovine plasma Suitable for manufacturing of diagnostic kits and reagents 750000UNITS ₹1957718.1 2022-06-14 Buy
Sigma-Aldrich(India) SRE0003 Thrombin from bovine plasma Suitable for manufacturing of diagnostic kits and reagents 70MU ₹3153199.2 2022-06-14 Buy
Sigma-Aldrich(India) SRE0003 Thrombin from bovine plasma Suitable for manufacturing of diagnostic kits and reagents 120MU ₹5405455.8 2022-06-14 Buy
Sigma-Aldrich(India) T6884 Thrombin from human plasma lyophilized powder, ≥2,000?NIH units/mg protein (E1%/280, 18.3) 1000UNITS ₹77222.7 2022-06-14 Buy
Sigma-Aldrich(India) T1063 Thrombin from human plasma lyophilized powder, ≥2800?NIH units/mg protein (E1%/280, 18.3) 1000UNITS ₹82728.3 2022-06-14 Buy

Properties

Melting point :47.7 °C
storage temp. :-20°C
solubility :H2O: 1 mL/vial clear to slightly hazy, colorless solution
form :powder
color :white
Merck :13,9461
EPA Substance Registry System :Thrombin (9002-04-4)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled Sensitisation, respiratory Category 1 Danger GHS hazard pictograms P261, P285, P304+P341, P342+P311,P501
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Thrombin is the last enzyme in the clotting cascade functioning to cleave fibrinogen to fibrin and potentiates the procoagulation process by activating factors V, VIII, XI, and XIII. Conversely, thrombin aids the anticoagulant process by activating protein C. Activated protein C inhibits activated factors V and VIII ultimately down-regulating further thrombin production. Thrombin is often used as a potent platelet activator in vitro. Platelet responses to thrombin are mediated through protease-activated receptors (PARs). Thrombin-mediated signaling regulates a diverse range of metabolic processes including activation of phospholipases in platelets, endothelial cells, and cardiac myocytes.

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