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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Metabolism >Transferase Inhibitors >Tipifarnib

Tipifarnib

Tipifarnib Structure
  • ₹13726.1 - ₹55077.6
  • Product name: Tipifarnib
  • CAS: 192185-72-1
  • MF: C27H22Cl2N4O
  • MW: 489.4
  • EINECS:
  • MDL Number:MFCD07772347
  • Synonyms:TIPIFARNIB;TIPIFARNIB ZARNESTRA;(R)-6-(Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl)-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone;Zarnestra;(R)-(+)-R 115777;6-[(R)-AMino(4-chlorophenyl)(1-Methyl-1H-iMidazol-5-yl)Methyl]-4-(3-chlorophenyl)-1-Methyl-2(1H)-quinolinone;Tipifarnib(Zarnestra,NSC-702818, R-115777);IND 58359
Price2 Properties Safety Information Description
2 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1668
  • Product descriptionTipifarnib ≥98% (HPLC)
  • Packaging5MG
  • Price₹13726.1
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1668
  • Product descriptionTipifarnib ≥98% (HPLC)
  • Packaging25MG
  • Price₹55077.6
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML1668 Tipifarnib ≥98% (HPLC) 5MG ₹13726.1 2022-06-14 Buy
Sigma-Aldrich(India) SML1668 Tipifarnib ≥98% (HPLC) 25MG ₹55077.6 2022-06-14 Buy

Properties

Melting point :211-213°C (dec.)
Boiling point :681.7±55.0 °C(Predicted)
Density :1.33±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Chloroform (Slightly), Methanol (Slightly)
pka :7.20±0.10(Predicted)
form :powder
color :white to beige
optical activity :[α]/D 17 to 24°, c = 1 in methanol

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

A farnesyltransferase inhibitor. Sensitizes human multiple myeloma cell to proteasome inhibition by blocking degradation of bortezomib(B675700)-induced aggresomes. Also shown to inhibit the growth of myeloid leukemia cell lines and primary leukemia cells by inducing apoptosis and cell-cycle blockage when combined with rapamycin(R124000).

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Suppliers and manufacturers

career henan chemical co
Tipifarnib
₹2.00 /1kg
Tipifarnib CAS:192185-72-1
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Dideu Industries Group Limited
Finetech Industry Limited